Heterogeneous growth and mental development of intrauterine growth-retarded infants during the first 3 years of life

J. Villar, V. Smeriglio, R. Martorell, C. H. Brown, R. E. Klein

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Abstract

Postnatal growth and development were studied in two groups of term infants with intrauterine growth retardation (IUGR) and one group of infants with normal birth weight up to 3 years of age (total sample, 205 infants). Infants with IUGR were classified as having low ponderal index (IUGR-LPI) or adequate ponderal index (IUGR-API). At birth, the two groups of infants with IUGR had similar birth weight, but length and head circumference measurements were significantly different. Overall, the IUGR-API infants remained lighter and shorter and had smaller head circumferences up to 30 months of age. The IUGR-LPI infants experienced catch-up growth in weight during the first months, because of greater fat deposition. At 24 months of age, the IUGR-API infants scored below the others on mental items. At 3 years of age the IUGR-API infants had the lowest values on seven of eight developmental measures and on the composite score; at these two time periods, the group with normal birth weight scored the highest, and the IUGR-LPI infants obtained intermediate values. It is concluded that infants with IUGR tend to follow postnatal growth and developmental patterns that are associated with their physical characteristics at birth.

Original languageEnglish
Pages (from-to)783-791
Number of pages9
JournalPediatrics
Volume74
Issue number5
StatePublished - Dec 1 1984

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Fetal Growth Retardation
Growth and Development
Growth
Birth Weight
Weights and Measures
Head
Parturition
Fats

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Villar, J., Smeriglio, V., Martorell, R., Brown, C. H., & Klein, R. E. (1984). Heterogeneous growth and mental development of intrauterine growth-retarded infants during the first 3 years of life. Pediatrics, 74(5), 783-791.

Heterogeneous growth and mental development of intrauterine growth-retarded infants during the first 3 years of life. / Villar, J.; Smeriglio, V.; Martorell, R.; Brown, C. H.; Klein, R. E.

In: Pediatrics, Vol. 74, No. 5, 01.12.1984, p. 783-791.

Research output: Contribution to journalArticle

Villar, J, Smeriglio, V, Martorell, R, Brown, CH & Klein, RE 1984, 'Heterogeneous growth and mental development of intrauterine growth-retarded infants during the first 3 years of life', Pediatrics, vol. 74, no. 5, pp. 783-791.
Villar J, Smeriglio V, Martorell R, Brown CH, Klein RE. Heterogeneous growth and mental development of intrauterine growth-retarded infants during the first 3 years of life. Pediatrics. 1984 Dec 1;74(5):783-791.
Villar, J. ; Smeriglio, V. ; Martorell, R. ; Brown, C. H. ; Klein, R. E. / Heterogeneous growth and mental development of intrauterine growth-retarded infants during the first 3 years of life. In: Pediatrics. 1984 ; Vol. 74, No. 5. pp. 783-791.
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