Herpes Simplex Virus Type 1: A Cause of the Acute Retinal Necrosis Syndrome

Mary Lou Lewis, William W. Culbertson, M. Judith D. Post, Darlene Miller, Gregg T. Kokame, Richard D. Dix

Research output: Contribution to journalArticle

111 Scopus citations

Abstract

The authors have isolated herpes simplex virus type 1 (HSV-1) from the vitreous of two patients with acute retinal necrosis. Clinical and laboratory data suggest that one case represented a primary HSV-1 infection, whereas the other case appeared to be a recurrent HSV-1 infection. In the primary case, changes on magnetic resonance imaging (MRI) suggest spread of the virus posteriorly to both optic tracts and the lateral geniculate ganglia. This case shares many features with the 'von Szily' expermental model for HSV retinitis in the mouse.

Original languageEnglish (US)
Pages (from-to)875-878
Number of pages4
JournalOphthalmology
Volume96
Issue number6
DOIs
StatePublished - Jan 1 1989

ASJC Scopus subject areas

  • Ophthalmology

Fingerprint Dive into the research topics of 'Herpes Simplex Virus Type 1: A Cause of the Acute Retinal Necrosis Syndrome'. Together they form a unique fingerprint.

  • Cite this