Hepatotoxicity of anesthetics and other central nervous system drugs

C. Holt, M. Csete, P. Martin

Research output: Contribution to journalReview articlepeer-review

18 Scopus citations


A large number of anesthetics, tranquilizers, hypnotic sedatives, and anticonvulsants are used clinically. Although these agents are generally well tolerated, liver injury of differing patterns is well recognized with their use. Knowledge of the likelihood of hepatotoxicity and the characteristic clinical features with these compounds is important as fatal outcomes due to liver failure have been reported with several of these agents. This article describes the potential mechanisms and clinical features of drug hepatotoxicity associated with these compounds.

Original languageEnglish (US)
Pages (from-to)853-874
Number of pages22
JournalGastroenterology Clinics of North America
Issue number4
StatePublished - Dec 1 1995
Externally publishedYes

ASJC Scopus subject areas

  • Gastroenterology


Dive into the research topics of 'Hepatotoxicity of anesthetics and other central nervous system drugs'. Together they form a unique fingerprint.

Cite this