Hepatosplenic Peliosis after Danazol and Glucocorticoids for ITP

Gideon Nesher, Leah Dollberg, Ari Zimran, Chaim Hershko, Yeon Ahn, William J. Harrington, Glenda M. Treadway

Research output: Contribution to journalLetter

29 Citations (Scopus)

Abstract

To the Editor: Danazol, a steroid with weak androgenic activity, was shown by Ahn et al. to be effective in patients with idiopathic thrombocytopenic purpura (ITP) not responding to splenectomy,1 and its place in the management of refractory ITP was discussed in a recent editorial in the Journal (April 19 issue).2 In view of the grave prognosis of severe refractory ITP, an increasing number of patients with ITP may be given this treatment in the future. It is in this context that the development of peliosis, a life-threatening complication of danazol treatment in one of our patients, should be noted.

Original languageEnglish (US)
Pages (from-to)242-243
Number of pages2
JournalNew England Journal of Medicine
Volume312
Issue number4
DOIs
StatePublished - Jan 24 1985
Externally publishedYes

Fingerprint

Danazol
Purpura
Idiopathic Thrombocytopenic Purpura
Glucocorticoids
Splenectomy
Steroids
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Nesher, G., Dollberg, L., Zimran, A., Hershko, C., Ahn, Y., Harrington, W. J., & Treadway, G. M. (1985). Hepatosplenic Peliosis after Danazol and Glucocorticoids for ITP. New England Journal of Medicine, 312(4), 242-243. https://doi.org/10.1056/NEJM198501243120413

Hepatosplenic Peliosis after Danazol and Glucocorticoids for ITP. / Nesher, Gideon; Dollberg, Leah; Zimran, Ari; Hershko, Chaim; Ahn, Yeon; Harrington, William J.; Treadway, Glenda M.

In: New England Journal of Medicine, Vol. 312, No. 4, 24.01.1985, p. 242-243.

Research output: Contribution to journalLetter

Nesher, G, Dollberg, L, Zimran, A, Hershko, C, Ahn, Y, Harrington, WJ & Treadway, GM 1985, 'Hepatosplenic Peliosis after Danazol and Glucocorticoids for ITP', New England Journal of Medicine, vol. 312, no. 4, pp. 242-243. https://doi.org/10.1056/NEJM198501243120413
Nesher G, Dollberg L, Zimran A, Hershko C, Ahn Y, Harrington WJ et al. Hepatosplenic Peliosis after Danazol and Glucocorticoids for ITP. New England Journal of Medicine. 1985 Jan 24;312(4):242-243. https://doi.org/10.1056/NEJM198501243120413
Nesher, Gideon ; Dollberg, Leah ; Zimran, Ari ; Hershko, Chaim ; Ahn, Yeon ; Harrington, William J. ; Treadway, Glenda M. / Hepatosplenic Peliosis after Danazol and Glucocorticoids for ITP. In: New England Journal of Medicine. 1985 ; Vol. 312, No. 4. pp. 242-243.
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