Hepatocellular carcinoma: CT and MR features after transcatheter arterial embolization and percutaneous ethanol injection

Carlo Bartolozzi, Riccardo Lencioni, Davide Caramella, Fabio Falaschi, Roberto Cioni, Giancarlo DiCoscio

Research output: Contribution to journalArticle

98 Scopus citations

Abstract

PURPOSE: To investigate the reliability of computed tomography (CT) and magnetic resonance (MR) imaging in the evaluation of the response of hepatocellular carcinoma (HCC) to transcatheter arterial embolization (TAE) followed by percutaneous ethanol injection (PEI). MATERIALS AND METHODS: Between January 1991 and November 1992, 20 patients (15 men and five women, aged 53-73 years [mean, 64.6 years]) with 31 HCC lesions underwent CT and MR imaging before and after treatment with combined TAE and PEI. RESULTS: Twenty-seven tumors, which were hypointense on posttreatment T2-weighted images and on gadolinium-enhanced T1-weighted images, were seen to be necrotic at biopsy. In four cases of incomplete necrosis, viable tumor was hyperintense on T2-weighted images and was enhanced after administration of contrast material. CT provided a larger spectrum of imaging features as a result of the presence of both hyperattenuating areas (caused by retention of iodized oil) and hypoattenuating areas (due to ethanol-induced necrosis). CONCLUSION: CT and MR imaging findings proved useful in the evaluation of the response of HCC to combined TAE and PEI.

Original languageEnglish (US)
Pages (from-to)123-128
Number of pages6
JournalRadiology
Volume191
Issue number1
DOIs
StatePublished - Apr 1994

Keywords

  • Alcohol
  • Liver neoplasms, therapy
  • Liver, CT
  • Liver, MR
  • Liver, interventional procedure

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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