Hepatitis C virus infection in a sexually active inner city population. The potential for heterosexual transmission

G. L. Daikos, S. Lai, M. A. Fischl

Research output: Contribution to journalArticlepeer-review

30 Scopus citations

Abstract

The prevalence of hepatitis C virus (HCV) infection and associated risk factors in an inner city sexually active heterosexual population participating in a prospective study for the evaluation of heterosexual transmission of human immunodeficiency virus type-1 (HIV-1) were examined. Individuals with prior history of injection drug use or receipt of blood products were excluded from the study. Of 571 participants, 25 (4.4%) were seropositive for HCV, 39 (7%) for HIV, and 125 (22%) for hepatitis B virus (HBV). Multivariate analysis revealed that those with more than ten heterosexual partners in the past 5 years (OR=3.7; 95% CI=1.3, 10.2; P=0.01), engaging in sexual practices more than once per week (OR=3.3; 95% CI=1.1, 10.1; P=0.04), with antibody to hepatitis B core (HBc) antigen (OR=2.9; 95% CI=1.1, 7.4; P=0.03), and antibody to HIV-1 (OR=5.8; 95% CI=1.9; 17.6; P=0.002) were independently associated with HCV infection. These findings suggest that heterosexual transmission of HCV may occur in an inner city sexually active heterosexual population.

Original languageEnglish (US)
Pages (from-to)72-76
Number of pages5
JournalInfection
Volume22
Issue number2
DOIs
StatePublished - Mar 1994

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

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