Hepatitis B virus infection and the dialysis patient

Fabrizio Fabrizi, Piergiorgio Messa, Paul Martin

Research output: Contribution to journalArticle

47 Citations (Scopus)

Abstract

Prevention of nosocomial transmission of hepatitis B virus (HBV) has been a signal achievement in the management of chronic kidney disease. The rate of serum hepatitis B surface antigen (HBsAg) seropositivity in patients on maintenance hemodialysis in the developed world is currently low (0-10%) but outbreaks of acute HBV infection continue to occur in this setting. The prevalence of HBV infection within dialysis units in developing countries appears higher (2-20%) based on relatively few reports. Although data are limited, HBV infection in dialysis population diminishes survival; HBV viral load in HBsAg-positive dialysis patients is reportedly low and stable over time. Updated recommendations for the management of HBsAg chronic carriers on maintenance dialysis have been issued. No rigorously controlled treatment trials for treatment of hepatitis B with either interferon or lamivudine therapy in dialysis patients are currently available.

Original languageEnglish
Pages (from-to)440-446
Number of pages7
JournalSeminars in Dialysis
Volume21
Issue number5
DOIs
StatePublished - Sep 1 2008

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Virus Diseases
Hepatitis B virus
Dialysis
Hepatitis B Surface Antigens
Maintenance
Lamivudine
Viral Load
Hepatitis B
Chronic Renal Insufficiency
Interferons
Developing Countries
Disease Outbreaks
Renal Dialysis
Therapeutics
Survival
Serum
Population

ASJC Scopus subject areas

  • Nephrology

Cite this

Hepatitis B virus infection and the dialysis patient. / Fabrizi, Fabrizio; Messa, Piergiorgio; Martin, Paul.

In: Seminars in Dialysis, Vol. 21, No. 5, 01.09.2008, p. 440-446.

Research output: Contribution to journalArticle

Fabrizi, Fabrizio ; Messa, Piergiorgio ; Martin, Paul. / Hepatitis B virus infection and the dialysis patient. In: Seminars in Dialysis. 2008 ; Vol. 21, No. 5. pp. 440-446.
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