Hepatitis B virus infection and primary hepatocellular carcinoma

E. Tabor, R. J. Gerety, Charles Vogel, A. C. Bayley, P. P. Anthony, C. H. Chan, L. F. Barker

Research output: Contribution to journalArticle

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Abstract

In 93 patients with biopsy proven primary hepatocellular carcinoma (PHC) from Uganda, Zambia, and the U.S.A. serologic evidence of hepatitis B virus (BHV) infection was sought for. Patients were tested for hepatitis B surface antigen (HBsAg) and its antibody (anti HBs), antibody to the hepatitis B core antigen (anti HBc), hepatitis B e antigen (HBeAg), and its antibody (anti HBe). Active HBV infection, as indicated by positive tests for HBsAg (with or without anti HBs) and anti HBc (without anti HBs), was present in 62% of PHC patients (58 of 93), in contrast with 10% of African controls (9 of 90), and less than 1% of most U.S.A. adult populations reported in the literature. The presence of HBeAg or anti HBe was rare among PHC patients and controls.

Original languageEnglish
Pages (from-to)1197-1200
Number of pages4
JournalJournal of the National Cancer Institute
Volume58
Issue number5
StatePublished - Dec 1 1977

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Virus Diseases
Hepatitis B virus
Hepatocellular Carcinoma
Hepatitis B Core Antigens
Anti-Idiotypic Antibodies
Hepatitis B e Antigens
Hepatitis B Surface Antigens
Zambia
Uganda
Biopsy
Antibodies
Infection
Population

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Tabor, E., Gerety, R. J., Vogel, C., Bayley, A. C., Anthony, P. P., Chan, C. H., & Barker, L. F. (1977). Hepatitis B virus infection and primary hepatocellular carcinoma. Journal of the National Cancer Institute, 58(5), 1197-1200.

Hepatitis B virus infection and primary hepatocellular carcinoma. / Tabor, E.; Gerety, R. J.; Vogel, Charles; Bayley, A. C.; Anthony, P. P.; Chan, C. H.; Barker, L. F.

In: Journal of the National Cancer Institute, Vol. 58, No. 5, 01.12.1977, p. 1197-1200.

Research output: Contribution to journalArticle

Tabor, E, Gerety, RJ, Vogel, C, Bayley, AC, Anthony, PP, Chan, CH & Barker, LF 1977, 'Hepatitis B virus infection and primary hepatocellular carcinoma', Journal of the National Cancer Institute, vol. 58, no. 5, pp. 1197-1200.
Tabor E, Gerety RJ, Vogel C, Bayley AC, Anthony PP, Chan CH et al. Hepatitis B virus infection and primary hepatocellular carcinoma. Journal of the National Cancer Institute. 1977 Dec 1;58(5):1197-1200.
Tabor, E. ; Gerety, R. J. ; Vogel, Charles ; Bayley, A. C. ; Anthony, P. P. ; Chan, C. H. ; Barker, L. F. / Hepatitis B virus infection and primary hepatocellular carcinoma. In: Journal of the National Cancer Institute. 1977 ; Vol. 58, No. 5. pp. 1197-1200.
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