Hemophagocytic, non-secretory multiple myeloma

David G. Savage, Deborah Zipin, Govind Bhagat, Bachir Alobeid

Research output: Contribution to journalArticle

15 Scopus citations

Abstract

A 70-year-old woman presented with pancytopenia associated with plasma cell infiltration of her bone marrow. The plasma cells were often multinucleated and demonstrated phagocytosis of erythroid and granulocytic cells. Atypical immunophenotypic features included the expression of CD117 and CD13 and the lack of expression of CD56. Although kappa chains were demonstrable in the cytoplasm, no paraprotein was found in the serum or urine. Osteolytic lesions were absent. The pancytopenia of this unusual patient with non-secretory, hemophagocytic myeloma has improved on dexamethasone monotherapy, although her hemophagocytosis persists.

Original languageEnglish (US)
Pages (from-to)1061-1064
Number of pages4
JournalLeukemia and Lymphoma
Volume45
Issue number5
DOIs
StatePublished - May 1 2004

Keywords

  • Hemophagocytosis
  • Multiple myeloma
  • Non-secretory

ASJC Scopus subject areas

  • Hematology
  • Oncology
  • Cancer Research

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  • Cite this

    Savage, D. G., Zipin, D., Bhagat, G., & Alobeid, B. (2004). Hemophagocytic, non-secretory multiple myeloma. Leukemia and Lymphoma, 45(5), 1061-1064. https://doi.org/10.1080/10428190310001623856