Hemophagocytic, non-secretory multiple myeloma

David G. Savage, Deborah Glick, Govind Bhagat, Bachir Alobeid

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

A 70-year-old woman presented with pancytopenia associated with plasma cell infiltration of her bone marrow. The plasma cells were often multinucleated and demonstrated phagocytosis of erythroid and granulocytic cells. Atypical immunophenotypic features included the expression of CD117 and CD13 and the lack of expression of CD56. Although kappa chains were demonstrable in the cytoplasm, no paraprotein was found in the serum or urine. Osteolytic lesions were absent. The pancytopenia of this unusual patient with non-secretory, hemophagocytic myeloma has improved on dexamethasone monotherapy, although her hemophagocytosis persists.

Original languageEnglish
Pages (from-to)1061-1064
Number of pages4
JournalLeukemia and Lymphoma
Volume45
Issue number5
DOIs
StatePublished - May 1 2004
Externally publishedYes

Fingerprint

Pancytopenia
Plasma Cells
Multiple Myeloma
Paraproteins
Erythroid Cells
Phagocytosis
Dexamethasone
Cytoplasm
Bone Marrow
Urine
Serum

Keywords

  • Hemophagocytosis
  • Multiple myeloma
  • Non-secretory

ASJC Scopus subject areas

  • Hematology
  • Oncology
  • Cancer Research

Cite this

Savage, D. G., Glick, D., Bhagat, G., & Alobeid, B. (2004). Hemophagocytic, non-secretory multiple myeloma. Leukemia and Lymphoma, 45(5), 1061-1064. https://doi.org/10.1080/10428190310001623856

Hemophagocytic, non-secretory multiple myeloma. / Savage, David G.; Glick, Deborah; Bhagat, Govind; Alobeid, Bachir.

In: Leukemia and Lymphoma, Vol. 45, No. 5, 01.05.2004, p. 1061-1064.

Research output: Contribution to journalArticle

Savage, DG, Glick, D, Bhagat, G & Alobeid, B 2004, 'Hemophagocytic, non-secretory multiple myeloma', Leukemia and Lymphoma, vol. 45, no. 5, pp. 1061-1064. https://doi.org/10.1080/10428190310001623856
Savage, David G. ; Glick, Deborah ; Bhagat, Govind ; Alobeid, Bachir. / Hemophagocytic, non-secretory multiple myeloma. In: Leukemia and Lymphoma. 2004 ; Vol. 45, No. 5. pp. 1061-1064.
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