An infant with ABO incompatibility and glucose-6-phosphate dehydrogenase deficiency developed severe intravascular hemolysis leading to hemoglobinuria in the immediate neonatal period. Severe intravascular hemolysis with resultant hemoglobinuria is rare in ABO hemolytic disease of the newborn. In vitro studies of the maternal serum demonstrated a complement dependent antibody which was capable of lysing normal B-positive erythrocytes.
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health