Hemiplegic migraine

M. Duchowny, L. Machado, D. Granado-Villar

Research output: Contribution to journalArticlepeer-review


Hemiplegic migraine is a rare disorder characterized by the association of migraine headache with hemiparesis and hemisensory loss. We describe the clinical course of an 8-year-old autistic boy who presented with rapidly evolving left-sided weakness and headache in the context of a nonspecific febrile illness. A comprehensive workup including detailed neuroimaging failed to identify a structural, biochemical or epileptic cause. He experienced complete resolution of his symptoms in 4 days and was discharged in stable condition. Hemiplegic migraine is an important mimicker of serious conditions producing neurologic injury but is rarely diagnosed at initial presentation and is clinically diagnosed by exclusion. The pathogenesis of this disorder is believed to involve episodic vasoconstriction of the middle cerebral artery. Linkage studies in familial cases have identified genetic loci on chromosomes 1 and 19.

Original languageEnglish (US)
Pages (from-to)51-53
Number of pages3
JournalInternational Pediatrics
Issue number1
StatePublished - Jan 1 1998


  • Headache
  • Hemiplegia
  • Migraine

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health


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