Hematoporphyrin photoradiation therapy for intraocular and orbital malignant melanoma

David Tse, J. J. Dutton, T. A. Weingeist, V. M. Hermsen, R. C. Kersten

Research output: Contribution to journalArticle

65 Citations (Scopus)

Abstract

Photoradiation therapy (PRT) is a new technique that is currently under investigation for the treatment of a variety of solid malignant tumors. The technique involves systemic administration of hematoporphyrin derivative (HpD), a photosensitizing compound that is preferentially retained by malignant cells and photoactivation of the neoplasm with red light (630 nm) to achieve selective destruction of cancer cells. We used HpD PRT for seven patients with malignant melanoma of the uvea and conclude that initial results of HpD PRT for uveal malignant melanoma are encouraging and justify further investigation.

Original languageEnglish
Pages (from-to)833-838
Number of pages6
JournalArchives of Ophthalmology
Volume102
Issue number6
StatePublished - Aug 2 1984
Externally publishedYes

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Hematoporphyrin Photoradiation
Hematoporphyrin Derivative
Phototherapy
Melanoma
Neoplasms
Light
Uveal melanoma

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Tse, D., Dutton, J. J., Weingeist, T. A., Hermsen, V. M., & Kersten, R. C. (1984). Hematoporphyrin photoradiation therapy for intraocular and orbital malignant melanoma. Archives of Ophthalmology, 102(6), 833-838.

Hematoporphyrin photoradiation therapy for intraocular and orbital malignant melanoma. / Tse, David; Dutton, J. J.; Weingeist, T. A.; Hermsen, V. M.; Kersten, R. C.

In: Archives of Ophthalmology, Vol. 102, No. 6, 02.08.1984, p. 833-838.

Research output: Contribution to journalArticle

Tse, D, Dutton, JJ, Weingeist, TA, Hermsen, VM & Kersten, RC 1984, 'Hematoporphyrin photoradiation therapy for intraocular and orbital malignant melanoma', Archives of Ophthalmology, vol. 102, no. 6, pp. 833-838.
Tse D, Dutton JJ, Weingeist TA, Hermsen VM, Kersten RC. Hematoporphyrin photoradiation therapy for intraocular and orbital malignant melanoma. Archives of Ophthalmology. 1984 Aug 2;102(6):833-838.
Tse, David ; Dutton, J. J. ; Weingeist, T. A. ; Hermsen, V. M. ; Kersten, R. C. / Hematoporphyrin photoradiation therapy for intraocular and orbital malignant melanoma. In: Archives of Ophthalmology. 1984 ; Vol. 102, No. 6. pp. 833-838.
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