Helical CT combined with contrast material administered only through the colon for imaging of suspected appendicitis

Patrick M. Rao, James T. Rhea, Robert A. Novelline, Amy A. Mostafavi, J. Nash Lawrason, Charles J. McCabe

Research output: Contribution to journalArticle

201 Citations (Scopus)

Abstract

OBJECTIVE. Helical CT combined with contrast material administered by mouth and through the colon has been shown to be accurate for appendiceal imaging. This investigation was performed to determine if helical CT combined with contrast material administered only through the colon has comparable accuracy. SUBJECTS AND METHODS. One hundred patients prospectively underwent appendiceal CT imaging with thin-collimation, helical scanning limited to the lower abdomen and upper pelvis after contrast material was administered only through the colon. CT results were correlated with surgical and pathologic findings at appendectomy (56 patients), other surgery (three patients), or clinical follow-up at least 2 months after the CT scan (41 patients). RESULTS. Fifty-three CT scans were interpreted as positive for appendicitis, including 52 true-positives (with surgical-pathologic correlation) and one false-positive (with clinical follow-up). Forty-seven CT scans were interpreted as negative for appendicitis, including 40 true-negatives with clinical follow-up, three true-negatives with appendectomy and pathologic correlation, three true-negatives with other surgery and pathologic correlation, and one false-negative with appendectomy and pathologic correlation. CT had a 98% sensitivity, 98% specificity, 98% positive predictive value, 98% negative predictive value, and 98% accuracy for diagnosing or excluding appendicitis. In 43 normal appendix cases at CT, the appendix was seen in 44 cases (94%), and an alternative diagnosis was identified in 29 cases (62%). CONCLUSION. For diagnosing appendicitis, helical CT combined with contrast material administered only through the colon proved to be as accurate (98%) as helical CT combined with contrast material administered by mouth and through the colon. Helical CT with contrast material administered only through the colon also could be performed immediately and without any of the potential patient risks or discomforts of contrast material administered IV or by mouth.

Original languageEnglish
Pages (from-to)1275-1280
Number of pages6
JournalAmerican Journal of Roentgenology
Volume169
Issue number5
StatePublished - Nov 1 1997

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Spiral Computed Tomography
Appendicitis
Contrast Media
Colon
Appendectomy
Mouth
Appendix
Pelvis
Abdomen
Sensitivity and Specificity

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Rao, P. M., Rhea, J. T., Novelline, R. A., Mostafavi, A. A., Lawrason, J. N., & McCabe, C. J. (1997). Helical CT combined with contrast material administered only through the colon for imaging of suspected appendicitis. American Journal of Roentgenology, 169(5), 1275-1280.

Helical CT combined with contrast material administered only through the colon for imaging of suspected appendicitis. / Rao, Patrick M.; Rhea, James T.; Novelline, Robert A.; Mostafavi, Amy A.; Lawrason, J. Nash; McCabe, Charles J.

In: American Journal of Roentgenology, Vol. 169, No. 5, 01.11.1997, p. 1275-1280.

Research output: Contribution to journalArticle

Rao, PM, Rhea, JT, Novelline, RA, Mostafavi, AA, Lawrason, JN & McCabe, CJ 1997, 'Helical CT combined with contrast material administered only through the colon for imaging of suspected appendicitis', American Journal of Roentgenology, vol. 169, no. 5, pp. 1275-1280.
Rao PM, Rhea JT, Novelline RA, Mostafavi AA, Lawrason JN, McCabe CJ. Helical CT combined with contrast material administered only through the colon for imaging of suspected appendicitis. American Journal of Roentgenology. 1997 Nov 1;169(5):1275-1280.
Rao, Patrick M. ; Rhea, James T. ; Novelline, Robert A. ; Mostafavi, Amy A. ; Lawrason, J. Nash ; McCabe, Charles J. / Helical CT combined with contrast material administered only through the colon for imaging of suspected appendicitis. In: American Journal of Roentgenology. 1997 ; Vol. 169, No. 5. pp. 1275-1280.
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abstract = "OBJECTIVE. Helical CT combined with contrast material administered by mouth and through the colon has been shown to be accurate for appendiceal imaging. This investigation was performed to determine if helical CT combined with contrast material administered only through the colon has comparable accuracy. SUBJECTS AND METHODS. One hundred patients prospectively underwent appendiceal CT imaging with thin-collimation, helical scanning limited to the lower abdomen and upper pelvis after contrast material was administered only through the colon. CT results were correlated with surgical and pathologic findings at appendectomy (56 patients), other surgery (three patients), or clinical follow-up at least 2 months after the CT scan (41 patients). RESULTS. Fifty-three CT scans were interpreted as positive for appendicitis, including 52 true-positives (with surgical-pathologic correlation) and one false-positive (with clinical follow-up). Forty-seven CT scans were interpreted as negative for appendicitis, including 40 true-negatives with clinical follow-up, three true-negatives with appendectomy and pathologic correlation, three true-negatives with other surgery and pathologic correlation, and one false-negative with appendectomy and pathologic correlation. CT had a 98{\%} sensitivity, 98{\%} specificity, 98{\%} positive predictive value, 98{\%} negative predictive value, and 98{\%} accuracy for diagnosing or excluding appendicitis. In 43 normal appendix cases at CT, the appendix was seen in 44 cases (94{\%}), and an alternative diagnosis was identified in 29 cases (62{\%}). CONCLUSION. For diagnosing appendicitis, helical CT combined with contrast material administered only through the colon proved to be as accurate (98{\%}) as helical CT combined with contrast material administered by mouth and through the colon. Helical CT with contrast material administered only through the colon also could be performed immediately and without any of the potential patient risks or discomforts of contrast material administered IV or by mouth.",
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AU - Rhea, James T.

AU - Novelline, Robert A.

AU - Mostafavi, Amy A.

AU - Lawrason, J. Nash

AU - McCabe, Charles J.

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N2 - OBJECTIVE. Helical CT combined with contrast material administered by mouth and through the colon has been shown to be accurate for appendiceal imaging. This investigation was performed to determine if helical CT combined with contrast material administered only through the colon has comparable accuracy. SUBJECTS AND METHODS. One hundred patients prospectively underwent appendiceal CT imaging with thin-collimation, helical scanning limited to the lower abdomen and upper pelvis after contrast material was administered only through the colon. CT results were correlated with surgical and pathologic findings at appendectomy (56 patients), other surgery (three patients), or clinical follow-up at least 2 months after the CT scan (41 patients). RESULTS. Fifty-three CT scans were interpreted as positive for appendicitis, including 52 true-positives (with surgical-pathologic correlation) and one false-positive (with clinical follow-up). Forty-seven CT scans were interpreted as negative for appendicitis, including 40 true-negatives with clinical follow-up, three true-negatives with appendectomy and pathologic correlation, three true-negatives with other surgery and pathologic correlation, and one false-negative with appendectomy and pathologic correlation. CT had a 98% sensitivity, 98% specificity, 98% positive predictive value, 98% negative predictive value, and 98% accuracy for diagnosing or excluding appendicitis. In 43 normal appendix cases at CT, the appendix was seen in 44 cases (94%), and an alternative diagnosis was identified in 29 cases (62%). CONCLUSION. For diagnosing appendicitis, helical CT combined with contrast material administered only through the colon proved to be as accurate (98%) as helical CT combined with contrast material administered by mouth and through the colon. Helical CT with contrast material administered only through the colon also could be performed immediately and without any of the potential patient risks or discomforts of contrast material administered IV or by mouth.

AB - OBJECTIVE. Helical CT combined with contrast material administered by mouth and through the colon has been shown to be accurate for appendiceal imaging. This investigation was performed to determine if helical CT combined with contrast material administered only through the colon has comparable accuracy. SUBJECTS AND METHODS. One hundred patients prospectively underwent appendiceal CT imaging with thin-collimation, helical scanning limited to the lower abdomen and upper pelvis after contrast material was administered only through the colon. CT results were correlated with surgical and pathologic findings at appendectomy (56 patients), other surgery (three patients), or clinical follow-up at least 2 months after the CT scan (41 patients). RESULTS. Fifty-three CT scans were interpreted as positive for appendicitis, including 52 true-positives (with surgical-pathologic correlation) and one false-positive (with clinical follow-up). Forty-seven CT scans were interpreted as negative for appendicitis, including 40 true-negatives with clinical follow-up, three true-negatives with appendectomy and pathologic correlation, three true-negatives with other surgery and pathologic correlation, and one false-negative with appendectomy and pathologic correlation. CT had a 98% sensitivity, 98% specificity, 98% positive predictive value, 98% negative predictive value, and 98% accuracy for diagnosing or excluding appendicitis. In 43 normal appendix cases at CT, the appendix was seen in 44 cases (94%), and an alternative diagnosis was identified in 29 cases (62%). CONCLUSION. For diagnosing appendicitis, helical CT combined with contrast material administered only through the colon proved to be as accurate (98%) as helical CT combined with contrast material administered by mouth and through the colon. Helical CT with contrast material administered only through the colon also could be performed immediately and without any of the potential patient risks or discomforts of contrast material administered IV or by mouth.

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