Helical chiral pyridine N- oxides: A new family of asymmetric catalysts

Jinshui Chen, Norito Takenaka

Research output: Contribution to journalArticle

74 Citations (Scopus)

Abstract

Optically active chiral alkyl chlorides are valuable compounds because of their bioactivity and versatile synthetic utility. Accordingly, the ring opening of epoxides with a chloride nucleophile stands as an important goal in asymmetric catalysis. We describe herein recent advances in the design and development of chiral pyridine N-oxide catalysts for the enantioselective synthesis of chlorohydrins,asymmetric catalysis atropisomerism chirality helical structures heterocycles.

Original languageEnglish (US)
Pages (from-to)7268-7276
Number of pages9
JournalChemistry - A European Journal
Volume15
Issue number30
DOIs
StatePublished - Jul 27 2009
Externally publishedYes

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Pyridine
Catalysis
Chlorides
Chlorohydrins
Nucleophiles
Catalysts
Oxides
Chirality
Epoxy Compounds
Bioactivity
pyridine N-oxide

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Helical chiral pyridine N- oxides : A new family of asymmetric catalysts. / Chen, Jinshui; Takenaka, Norito.

In: Chemistry - A European Journal, Vol. 15, No. 30, 27.07.2009, p. 7268-7276.

Research output: Contribution to journalArticle

Chen, Jinshui ; Takenaka, Norito. / Helical chiral pyridine N- oxides : A new family of asymmetric catalysts. In: Chemistry - A European Journal. 2009 ; Vol. 15, No. 30. pp. 7268-7276.
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