Helical chiral 2,2′-bipyridine N-monoxides as catalysts in the enantioselective propargylation of aldehydes with allenyltrichlorosilane

Jinshui Chen, Burjor Captain, Norito Takenaka

Research output: Contribution to journalArticle

93 Citations (Scopus)

Abstract

A highly enantioselective synthesis of homopropargylic alcohols is achieved by using the new helical chiral 2,2′-bipyridine N-monoxide catalyst and allenyltrichlorosilane. This method can be further extended to the enantio- and regioselective propargylation of N-acylhydrazones.

Original languageEnglish
Pages (from-to)1654-1657
Number of pages4
JournalOrganic Letters
Volume13
Issue number7
DOIs
StatePublished - Apr 1 2011

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aldehydes
Aldehydes
alcohols
Alcohols
catalysts
Catalysts
synthesis

ASJC Scopus subject areas

  • Organic Chemistry
  • Physical and Theoretical Chemistry
  • Biochemistry

Cite this

Helical chiral 2,2′-bipyridine N-monoxides as catalysts in the enantioselective propargylation of aldehydes with allenyltrichlorosilane. / Chen, Jinshui; Captain, Burjor; Takenaka, Norito.

In: Organic Letters, Vol. 13, No. 7, 01.04.2011, p. 1654-1657.

Research output: Contribution to journalArticle

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