Health-related quality of life after coronary artery bypass grafting: A gender analysis using the Duke Activity Status Index

Colleen Gorman Koch, Farah Khandwala, Jacek B. Cywinski, Hemant Ishwaran, Fawzy G. Estafanous, Floyd D. Loop, Eugene H. Blackstone

Research output: Contribution to journalArticle

53 Citations (Scopus)

Abstract

Objective Our objectives were to document the preoperative and postoperative functional status of patients undergoing coronary artery bypass grafting, to examine factors that influence functional recovery, and to determine whether gender differences exist in the preoperative and postoperative functional status with the Duke Activity Status Index. Methods One thousand eight hundred twenty-five patients undergoing isolated coronary artery bypass grafting had baseline and follow-up quality-of-life surveys. Mean follow-up from baseline to postoperative Duke Activity Status Index was 8.0 months for women and men. The influence of 47 variables, in addition to baseline scores on postoperative functional status, was examined with logistic ordinal modeling. An ordinal model for the follow-up score was determined by means of backward selection, with variables retained if they satisfied the criterion of a P value of less than .05. Results Median baseline Duke Activity Status Index scores (women, 21.5; men, 32.2; P < .001) and first follow-up scores (women, 42.7; men, 58.2; P < .001) were lower in women than in men. Patients who were older and those who had chronic obstructive pulmonary disease, myocardial infarction, stroke, diabetes, vascular disease, postoperative serious infection, and return to the operating room had lower postoperative scores. After adjusting for these factors, women still had lower follow-up scores (odds ratio for men, 2.1 [95% confidence interval, 1.7-2.6]; P < .001). Conclusions A number of preoperative factors, operative variables, and postoperative events are associated with functional recovery after coronary revascularization. In addition, female gender is associated with more postoperative functional impairment after adjusting for these perioperative variables.

Original languageEnglish
Pages (from-to)284-295
Number of pages12
JournalJournal of Thoracic and Cardiovascular Surgery
Volume128
Issue number2
DOIs
StatePublished - Aug 1 2004
Externally publishedYes

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Coronary Artery Bypass
Quality of Life
Operating Rooms
Vascular Diseases
Chronic Obstructive Pulmonary Disease
Stroke
Odds Ratio
Myocardial Infarction
Confidence Intervals
Infection

Keywords

  • 17
  • 18
  • 23

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Surgery

Cite this

Health-related quality of life after coronary artery bypass grafting : A gender analysis using the Duke Activity Status Index. / Koch, Colleen Gorman; Khandwala, Farah; Cywinski, Jacek B.; Ishwaran, Hemant; Estafanous, Fawzy G.; Loop, Floyd D.; Blackstone, Eugene H.

In: Journal of Thoracic and Cardiovascular Surgery, Vol. 128, No. 2, 01.08.2004, p. 284-295.

Research output: Contribution to journalArticle

Koch, Colleen Gorman ; Khandwala, Farah ; Cywinski, Jacek B. ; Ishwaran, Hemant ; Estafanous, Fawzy G. ; Loop, Floyd D. ; Blackstone, Eugene H. / Health-related quality of life after coronary artery bypass grafting : A gender analysis using the Duke Activity Status Index. In: Journal of Thoracic and Cardiovascular Surgery. 2004 ; Vol. 128, No. 2. pp. 284-295.
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