HCV testing: Order and completion rates among baby boomers obtaining care from seven health systems in Florida, 2015–2017

Susan T. Vadaparampil, Lindsay N. Fuzzell, Julie Rathwell, Richard R. Reich, Elizabeth Shenkman, David R. Nelson, Erin Kobetz, Patricia D. Jones, Richard Roetzheim, Anna R. Giuliano

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Many U.S. residents infected with hepatitis C virus (HCV) are baby boomers (born 1945–1965), who remain undiagnosed. Past CDC and USPSTF guidelines recommended one-time HCV testing for all baby boomers, with newer guidelines recommending universal screening for all adults. This retrospective cohort study examined electronic medical records for patient visits from 2015 to 2017 within the OneFlorida Data Trust and University of South Florida Health system. We assessed percentages of HCV tests ordered and completed across four age groups (those born before 1945, 1945–1965, 1966–1985, and after 1985). In 2019, we used logistic regression to examine factors associated with HCV test ordering and completion among baby boomers, including age, race, sex, number of primary care visits, HIV status, hepatitis diagnosis, and liver cancer history. All age groups had low rates of HCV test orders. 4.4% of baby boomers had a test ordered in 2015, and 6.7% in 2016. Of those, 94.5% and 89.7% completed testing, respectively. All other races/ethnicities had lower likelihood of testing completion than Whites (Blacks (aOR 0.82, 95%, CI 0.75–0.91); Asians (0.69, 0.52–0.92); Hispanics (0.29, 0.26–0.32)), although test orders were higher for Asians (1.48, 1.37–1.61) and Blacks (1.78, 1.73–1.82). Tests ordered (11.42, 10.94–11.92) and completed (2.25, 1.94–2.60) were more likely among those with hepatitis history. Test orders were more likely for HIV-positive patients (3.68, 3.45–3.93), but completion was less likely (0.67, 0.57–0.78). Interventions are needed to increase testing rates so that HCV infections are treated early, mitigating HCV-related morbidity and mortality, especially related to liver cancer.

Original languageEnglish (US)
Article number106222
JournalPreventive medicine
StatePublished - Dec 2021


  • Hepatitis C
  • Hepatitis C test

ASJC Scopus subject areas

  • Epidemiology
  • Public Health, Environmental and Occupational Health


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