Harvard HIV and aging workshop: Perspectives and Priorities from Claude D. Pepper Centers and Centers for AIDS Research

Monty Montano, Shalender Bhasin, Richard T. D'Aquila, Kristine M. Erlandson, William J. Evans, Nicholas T. Funderburg, Amy Justice, Lishomwa C. Ndhlovu, Bisola Ojikutu, Marco Pahor, Savita Pahwa, Alice S. Ryan, Jennifer Schrack, Michael B. Schultz, Paola Sebastiani, David A. Sinclair, Julia Tripp, Bruce Walker, Julie A. Womack, Raymond YungR. Keith Reeves

Research output: Contribution to journalArticle

Abstract

People aging with HIV (PAWH) infection experience greater impairments in physical and cognitive function, in addition to higher rates of peripheral comorbid conditions (e.g., renal failure, diabetes, bone fracture, hypertension, cardiovascular disease, polypharmacy, and multimorbidity). While multifactorial drivers, including HIV infection itself, antiretroviral therapy-related toxicities, disparities in care, and biobehavioral factors, likely contribute, there remains an overarching question as to what are the relevant age-related mechanisms and models that could inform interventions that promote health span and life span in PAWH This workshop was convened to hear from experts on the biology of aging and HIV researchers studying PAWH to focus on advancing investigations at the interface of HIV and Aging. In this study, we summarize the discussions from the Harvard Center for AIDS Research and Boston Claude D. Pepper cosponsored workshop on HIV and Aging, which took place in October 2018.

Original languageEnglish (US)
Pages (from-to)999-1012
Number of pages14
JournalAIDS research and human retroviruses
Volume35
Issue number11-12
DOIs
StatePublished - Nov 1 2019

Keywords

  • HIV
  • aging
  • frailty
  • immune activation

ASJC Scopus subject areas

  • Immunology
  • Virology
  • Infectious Diseases

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    Montano, M., Bhasin, S., D'Aquila, R. T., Erlandson, K. M., Evans, W. J., Funderburg, N. T., Justice, A., Ndhlovu, L. C., Ojikutu, B., Pahor, M., Pahwa, S., Ryan, A. S., Schrack, J., Schultz, M. B., Sebastiani, P., Sinclair, D. A., Tripp, J., Walker, B., Womack, J. A., ... Reeves, R. K. (2019). Harvard HIV and aging workshop: Perspectives and Priorities from Claude D. Pepper Centers and Centers for AIDS Research. AIDS research and human retroviruses, 35(11-12), 999-1012. https://doi.org/10.1089/aid.2019.0130