Hábito de fumar y enfermedad de Parkinson idiopática. Estudio caso-control

José Luis Giroud Benítez, Fernando Collado Mesa

Research output: Contribution to journalArticlepeer-review


It has been stated that idiopathic Parkinson's disease and smoking are inversely related, the second being considered as a "protective" factor. A non-paired case-control study was conducted in persons aged over 50 years to confirm the above-mentioned. To find the required sample size, we used the Epi Info Version 6.0 program, called Statcal, which determined that the necessary sample size should be 68 in 272. This was calculated on the basis of a case-control ratio of 1:4. Cigarette smoking was the analyzed variable that was divided into non-smokers, smokers and former smokers. It was verified that the relationship of non-smoker and smokers showed an RO = 3.34 (CI 1,36-8,88) statistically significant; p < 0,029. The rest of the possible combinations were not significant. Our study demonstrated that cigarette smoking and idiopathic Parkinson's disease are inversely related.

Original languageSpanish
Pages (from-to)16-19
Number of pages4
JournalRevista Cubana de Medicina
Issue number1
StatePublished - Dec 1 2002
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)

Cite this