Gynecology: Combined radiotherapy and chemotherapy in gynecologic oncology

Luther W. Brady, Arnold M. Markoe, Timothy Deems, George C. Lewis

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


In 1986, 930,000 new cases of invasive cancer were anticipated to be diagnosed in the United States. During the same time period, the following numbers of gynecologic cases were to be diagnosed: 1. 45,000 cases of carcinoma in situ of the cervix. 2. 14,000 new cases of invasive carcinoma of the cervix. 3. 36,000 new cases of cancers of the corpus-endometrium. 4. 19,000 new cases of carcinoma of the ovary. 5. 4,400 new cases of other and unspecified genital tract. This represents a total of 73,400 cases of invasive gynecologic cancer and 45,000 cases of in-situ carcinoma of the uterine cervix to be seen in 1986, constituting 15% of all cancers and about 9% of all cancers in women. The desired principle of multidiscipline management for gynecologic cancer is now well established. The best results in treatment may be anticipated when the treatment is carried out by physicians well acquainted with pelvic anatomy, the characteristics of the malignant disease, and the modalities to be used, whether surgery, radiation therapy, or chemotherapy. However, radiation therapy remains the most generally applicable method for control of gynecologic cancer. At present, these malignant tumors are being discovered earlier and emphasis on the importance of surgery in the management of the early disease is increasing. As an example, more than 75% of all invasive cancers of the cervix are now Stage I and II. In dealing with the wide variety of gynecologic cancers, extreme care must be exercised to choose the appropriate treatment program for each problem since undertreatment or overtreatment are equally undesirable. Each treatment technique may have severe or fatal sequelae if inappropriately used.

Original languageEnglish (US)
Pages (from-to)S203-S209
JournalInternational Journal of Radiation Oncology, Biology, Physics
Issue numberSUPPL. 1
StatePublished - 1988
Externally publishedYes

ASJC Scopus subject areas

  • Radiation
  • Oncology
  • Radiology Nuclear Medicine and imaging
  • Cancer Research


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