Guidelines for Auditory Threshold Measurement for Significant Threshold Shift

Kathleen Campbell, Tanisha Hammill, Michael E Hoffer, Jonathan Kil, Colleen Le Prell

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


The purpose of this article is to provide guidelines for determining a Significant Noise-Induced Threshold Shift in clinical trials involving human populations. The article reviews recommendations for the standards to be referenced for human subjects, equipment, test environment, and personnel. Additional guidelines for military populations are provided. Guidelines for the calibration of audiometers, sound booth noise levels, and immitance equipment are provided. In addition the guidance provides specific suggestions for the subjects history before study onset, and otoscopy. Test frequencies for threshold determination and methods of threshold determination are reviewed for both air conduction and bone conduction for both baseline testing and later determination of either a temporary (TTS) or permanent threshold shift (PTS). Once a Significant Noise-Induced Threshold Shift has been determined, subjects should be retested, conductive component should be ruled out or addressed, and the subject should be counseled or referred for additional medical evaluation. Guidance for reporting procedures and the computerized study database are described. Finally, experimental designs suggested for noise-induced otoprotection clinical trials are described.

Original languageEnglish (US)
Pages (from-to)e263-e270
JournalOtology and Neurotology
Issue number8
StatePublished - Sep 1 2016


  • Auditory
  • Measurement
  • Significant Threshold Shift
  • STS

ASJC Scopus subject areas

  • Medicine(all)
  • Otorhinolaryngology
  • Sensory Systems
  • Clinical Neurology


Dive into the research topics of 'Guidelines for Auditory Threshold Measurement for Significant Threshold Shift'. Together they form a unique fingerprint.

Cite this