Abstract
This review summarizes current thinking and evidence-based recommendations for pharmacotherapy in the treatment of dyslipidemia, metabolic syndrome, and glucose intolerance as a basis for their application to individuals with a spinal cord injury (SCI). Although the evidence that subjects with an SCI are categorically at increased risk for cardiovascular disease is mixed, a significant number of such patients have cardiometabolic risk factors and therefore a systematic approach to this problem is important. The guidelines discussed are those recommended by the Adult Treatment Panel III of the National Cholesterol Education Program. These focus primarily on low-density lipoprotein LDL cholesterol (LDL-C). Several cardiometabolic risk factors such as hypertriglyceridemia, low high-density lipoprotein cholesterol (HDL-C), and glucose intolerance constitute possible targets for pharmacotherapy beyond LDL-C.
Original language | English (US) |
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Pages (from-to) | 46-57 |
Number of pages | 12 |
Journal | Topics in Spinal Cord Injury Rehabilitation |
Volume | 14 |
Issue number | 3 |
DOIs | |
State | Published - Dec 1 2009 |
Keywords
- Dyslipidemia
- Glucose intolerance
- Metabolic syndrome
- Pharmacotherapy
ASJC Scopus subject areas
- Clinical Neurology
- Rehabilitation
- Physical Therapy, Sports Therapy and Rehabilitation