TY - JOUR
T1 - Growth hormone-releasing activity in the hypothalamus of animals of different species
AU - Muller, Eugenio E.
AU - Sawano, Shinji
AU - Schally, Andrew V.
PY - 1967/12
Y1 - 1967/12
N2 - Hypothalamic extracts from the dog, rabbit, mouse, kitten, pigeon, and frog were found to decrease the growth hormone (GH) content of rat pituitary glands. Comparable cerebral cortical extracts were completely inactive in this test. These results broaden previous observations on the existence of a GH-releasing factor (GRF) in the hypothalami of mammals and show the presence of GRF activity in birds and amphibians.
AB - Hypothalamic extracts from the dog, rabbit, mouse, kitten, pigeon, and frog were found to decrease the growth hormone (GH) content of rat pituitary glands. Comparable cerebral cortical extracts were completely inactive in this test. These results broaden previous observations on the existence of a GH-releasing factor (GRF) in the hypothalami of mammals and show the presence of GRF activity in birds and amphibians.
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U2 - 10.1016/0016-6480(67)90029-9
DO - 10.1016/0016-6480(67)90029-9
M3 - Article
C2 - 4867733
AN - SCOPUS:0014184307
VL - 9
SP - 349
EP - 352
JO - General and Comparative Endocrinology
JF - General and Comparative Endocrinology
SN - 0016-6480
IS - 3
ER -