Growth and body composition in children infected with the human immunodeficiency virus-1

T. L. Miller, S. J. Evans, E. J. Orav, V. Morris, K. McIntosh, H. S. Winter

Research output: Contribution to journalArticle

101 Scopus citations

Abstract

Anthropometric data were collected on 89 children born to human immunodeficiency virus (HIV)-infected women (37 who seroreverted and 52 who were HIV-infected). The main outcomes included birth weight, gestational age, weight, height, arm muscle circumference (AMC), and triceps skinfold thickness (TSF). Gestational age and birth weight were not different between the two groups. The earliest anthropometric evaluation on seroreverted children (age 19 mo) when compared with HIV-infected children (age 21 mo) revealed that weight and weight-for-height percentiles were significantly different (51% vs 33% and 66% vs 48%, respectively). Height and TSF percentiles were not different, although AMC percentiles were lower in infected children (64% vs 43%). In follow-up evaluations, the weight differences between infected and control children did not change. We conclude that HIV does not affect birth weight, but postnatal events result in altered weight gain in HIV-infected children. Lean body mass is lower than in an HIV-negative comparison group at early stages of HIV infection.

Original languageEnglish (US)
Pages (from-to)588-592
Number of pages5
JournalAmerican Journal of Clinical Nutrition
Volume57
Issue number4
DOIs
StatePublished - Jan 1 1993

Keywords

  • Acquired immunodeficiency
  • Body composition
  • Children
  • Growth
  • HIV

ASJC Scopus subject areas

  • Food Science
  • Medicine (miscellaneous)

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    Miller, T. L., Evans, S. J., Orav, E. J., Morris, V., McIntosh, K., & Winter, H. S. (1993). Growth and body composition in children infected with the human immunodeficiency virus-1. American Journal of Clinical Nutrition, 57(4), 588-592. https://doi.org/10.1093/ajcn/57.4.588