Graves' Disease and Pulmonary Hypertension: Report of 2 Cases

Salim S. Virani; Cesar E. Mendoza; Alexandre C. Ferreira; Eduardo De Marchena

Graves' Disease and Pulmonary Hypertension: Report of 2 Cases

Salim S. Virani, Cesar E. Mendoza, Alexandre C. Ferreira, Eduardo De Marchena

Medicine

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

A possible association between hyperthyroidism and pulmonary hypertension has been reported. We describe 2 patients who had pulmonary hypertension associated with Graves' disease, both of whom experienced prompt hemodynamic and symptomatic recovery after normal thyroid function was restored. An autoimmune mechanism associated with vascular endothelial damage appears to have played a key pathogenic role in the development of pulmonary hypertension in these patients.

Original language	English (US)
Pages (from-to)	314-315
Number of pages	2
Journal	Texas Heart Institute Journal
Volume	30
Issue number	4
State	Published - Dec 16 2003

Keywords

Autoimmune diseases/complications
Endothelium, vascular/injury
Graves' disease/complications/drug therapy
Hypertension, pulmonary
Hyperthyroidism/complications

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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abstract = "A possible association between hyperthyroidism and pulmonary hypertension has been reported. We describe 2 patients who had pulmonary hypertension associated with Graves' disease, both of whom experienced prompt hemodynamic and symptomatic recovery after normal thyroid function was restored. An autoimmune mechanism associated with vascular endothelial damage appears to have played a key pathogenic role in the development of pulmonary hypertension in these patients.",

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