Graves' Disease and Pulmonary Hypertension: Report of 2 Cases

Salim S. Virani, Cesar E. Mendoza, Alexandre C. Ferreira, Eduardo De Marchena

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


A possible association between hyperthyroidism and pulmonary hypertension has been reported. We describe 2 patients who had pulmonary hypertension associated with Graves' disease, both of whom experienced prompt hemodynamic and symptomatic recovery after normal thyroid function was restored. An autoimmune mechanism associated with vascular endothelial damage appears to have played a key pathogenic role in the development of pulmonary hypertension in these patients.

Original languageEnglish (US)
Pages (from-to)314-315
Number of pages2
JournalTexas Heart Institute Journal
Issue number4
StatePublished - Dec 16 2003


  • Autoimmune diseases/complications
  • Endothelium, vascular/injury
  • Graves' disease/complications/drug therapy
  • Hypertension, pulmonary
  • Hyperthyroidism/complications

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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