Abstract
Purpose: The purpose of this study was to provide 24-month followup on surgical success and safety of an ab interno circumferential 360-degree trabeculotomy. Methods: Chart review of patients who underwent a gonioscopyassisted transluminal trabeculotomy (GATT) procedure was performed by 4 of the authors (D.S.G., O.S., R.L.F., and D.G.G.). The surgery was performed in adults with various types of open-Angle glaucoma with preoperative intraocular pressures (IOPs) of ≥ 18mmHg. Results: In total, 198 patients aged 24 to 89 years underwent the GATT procedure with at least 18 months follow-up. Patients with primary open-Angle glaucoma had an average IOP decrease of 9.2mmHg at 24 months with an average decrease of 1.43 glaucoma medications. The mean percentage of IOP decrease in these primary open-Angle glaucoma groups at 24 months was 37.3%. In secondary open-Angle glaucoma, at 24 months there was an average decrease in IOP of 14.1mmHg on an average of 2.0 fewer medications. The mean percentage of IOP decrease in the secondary open-Angle glaucoma groups at 24 months was 49.8%. The cumulative proportion of failure at 24 months ranged from 0.18 to 0.48, depending on the group. In all 6 study groups, at all 5 postoperative time points (3, 6, 12, 18, and 24 mo) the mean IOP and reduction in glaucoma medications was significantly reduced from baseline (P< 0.001) with the exception of one time point. Conclusions: The 24-month results demonstrate that GATT is relatively safe and effective in treating various forms of open-Angle glaucoma. The long-Term results for GATT are relatively equivalent to those previously reported for GATT and ab externo trabeculotomy studies.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 393-401 |
| Number of pages | 9 |
| Journal | Journal of Glaucoma |
| Volume | 27 |
| Issue number | 5 |
| DOIs | |
| State | Published - Jan 1 2018 |
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Keywords
- Ab interno
- Circumferential trabeculotomy
- GATT
- Gonioscopy-Assisted transluminal trabeculotomy
ASJC Scopus subject areas
- Ophthalmology
Cite this
Gonioscopy-Assisted transluminal trabeculotomy : An ab interno circumferential trabeculotomy: 24 months follow-up. / Grover, Davinder S.; Smith, Oluwatosin; Fellman, Ronald L.; Godfrey, David G.; Gupta, Aditi; De Oca, Ildamaris Montes; Feuer, William J.
In: Journal of Glaucoma, Vol. 27, No. 5, 01.01.2018, p. 393-401.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Gonioscopy-Assisted transluminal trabeculotomy
T2 - An ab interno circumferential trabeculotomy: 24 months follow-up
AU - Grover, Davinder S.
AU - Smith, Oluwatosin
AU - Fellman, Ronald L.
AU - Godfrey, David G.
AU - Gupta, Aditi
AU - De Oca, Ildamaris Montes
AU - Feuer, William J
PY - 2018/1/1
Y1 - 2018/1/1
N2 - Purpose: The purpose of this study was to provide 24-month followup on surgical success and safety of an ab interno circumferential 360-degree trabeculotomy. Methods: Chart review of patients who underwent a gonioscopyassisted transluminal trabeculotomy (GATT) procedure was performed by 4 of the authors (D.S.G., O.S., R.L.F., and D.G.G.). The surgery was performed in adults with various types of open-Angle glaucoma with preoperative intraocular pressures (IOPs) of ≥ 18mmHg. Results: In total, 198 patients aged 24 to 89 years underwent the GATT procedure with at least 18 months follow-up. Patients with primary open-Angle glaucoma had an average IOP decrease of 9.2mmHg at 24 months with an average decrease of 1.43 glaucoma medications. The mean percentage of IOP decrease in these primary open-Angle glaucoma groups at 24 months was 37.3%. In secondary open-Angle glaucoma, at 24 months there was an average decrease in IOP of 14.1mmHg on an average of 2.0 fewer medications. The mean percentage of IOP decrease in the secondary open-Angle glaucoma groups at 24 months was 49.8%. The cumulative proportion of failure at 24 months ranged from 0.18 to 0.48, depending on the group. In all 6 study groups, at all 5 postoperative time points (3, 6, 12, 18, and 24 mo) the mean IOP and reduction in glaucoma medications was significantly reduced from baseline (P< 0.001) with the exception of one time point. Conclusions: The 24-month results demonstrate that GATT is relatively safe and effective in treating various forms of open-Angle glaucoma. The long-Term results for GATT are relatively equivalent to those previously reported for GATT and ab externo trabeculotomy studies.
AB - Purpose: The purpose of this study was to provide 24-month followup on surgical success and safety of an ab interno circumferential 360-degree trabeculotomy. Methods: Chart review of patients who underwent a gonioscopyassisted transluminal trabeculotomy (GATT) procedure was performed by 4 of the authors (D.S.G., O.S., R.L.F., and D.G.G.). The surgery was performed in adults with various types of open-Angle glaucoma with preoperative intraocular pressures (IOPs) of ≥ 18mmHg. Results: In total, 198 patients aged 24 to 89 years underwent the GATT procedure with at least 18 months follow-up. Patients with primary open-Angle glaucoma had an average IOP decrease of 9.2mmHg at 24 months with an average decrease of 1.43 glaucoma medications. The mean percentage of IOP decrease in these primary open-Angle glaucoma groups at 24 months was 37.3%. In secondary open-Angle glaucoma, at 24 months there was an average decrease in IOP of 14.1mmHg on an average of 2.0 fewer medications. The mean percentage of IOP decrease in the secondary open-Angle glaucoma groups at 24 months was 49.8%. The cumulative proportion of failure at 24 months ranged from 0.18 to 0.48, depending on the group. In all 6 study groups, at all 5 postoperative time points (3, 6, 12, 18, and 24 mo) the mean IOP and reduction in glaucoma medications was significantly reduced from baseline (P< 0.001) with the exception of one time point. Conclusions: The 24-month results demonstrate that GATT is relatively safe and effective in treating various forms of open-Angle glaucoma. The long-Term results for GATT are relatively equivalent to those previously reported for GATT and ab externo trabeculotomy studies.
KW - Ab interno
KW - Circumferential trabeculotomy
KW - GATT
KW - Gonioscopy-Assisted transluminal trabeculotomy
UR - http://www.scopus.com/inward/record.url?scp=85046882195&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85046882195&partnerID=8YFLogxK
U2 - 10.1097/IJG.0000000000000956
DO - 10.1097/IJG.0000000000000956
M3 - Article
AN - SCOPUS:85046882195
VL - 27
SP - 393
EP - 401
JO - Journal of Glaucoma
JF - Journal of Glaucoma
SN - 1057-0829
IS - 5
ER -