Gonioscopy assisted transluminal trabeculotomy: An ab interno circumferential trabeculotomy for the treatment of primary congenital glaucoma and juvenile open angle glaucoma

Davinder S. Grover, Oluwatosin Smith, Ronald L. Fellman, David G. Godfrey, Michelle R. Butler, Ildamaris Montes De Oca, William J Feuer

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

Background/aims To introduce a novel ab interno 360° trabeculotomy for treating primary congenital glaucoma (PCG) and juvenile open angle glaucoma ( JOAG) and report preliminary results. Methods A retrospective chart review of patients who underwent a gonioscopy assisted transluminal trabeculotomy (GATT) procedure by four of the authors (DSG, OS, RLF and DGG) between October 2011 and October 2013. The surgery was performed in patients ≤30 years old with a dysgenic anterior segment angle and uncontrolled PCG and JOAG. Results Fourteen eyes of 10 patients underwent GATT with follow-up >12 months (12-33 months; mean 20.4). Patients ranged in age from 17 months to 30 years (mean=18.4 years), and five (50%) were female patients. No complications occurred during or following surgery except for early postoperative hyphema in five (36%) of eyes, all cleared by 1 month. The mean intraocular pressure (IOP) decreased from 27.3 to 14.8 mm Hg and the mean number of medications required decreased from 2.6 to 0.86. Five eyes had a drop in IOP ≥15 mm Hg (range 15-39). Conclusions The preliminary results and safety for GATT, a minimally invasive conjunctival sparing circumferential trabeculotomy, are promising and at least equivalent to previous results for ab externo trabeculotomy for the treatment of PCG and JOAG. All eyes in the study were considered a clinical success.

Original languageEnglish (US)
Pages (from-to)1092-1096
Number of pages5
JournalBritish Journal of Ophthalmology
Volume99
Issue number8
DOIs
StatePublished - Aug 1 2015

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Gonioscopy
Trabeculectomy
Open Angle Glaucoma
Glaucoma
Intraocular Pressure
Therapeutics
Hyphema
Safety

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience

Cite this

Gonioscopy assisted transluminal trabeculotomy : An ab interno circumferential trabeculotomy for the treatment of primary congenital glaucoma and juvenile open angle glaucoma. / Grover, Davinder S.; Smith, Oluwatosin; Fellman, Ronald L.; Godfrey, David G.; Butler, Michelle R.; De Oca, Ildamaris Montes; Feuer, William J.

In: British Journal of Ophthalmology, Vol. 99, No. 8, 01.08.2015, p. 1092-1096.

Research output: Contribution to journalArticle

Grover, Davinder S. ; Smith, Oluwatosin ; Fellman, Ronald L. ; Godfrey, David G. ; Butler, Michelle R. ; De Oca, Ildamaris Montes ; Feuer, William J. / Gonioscopy assisted transluminal trabeculotomy : An ab interno circumferential trabeculotomy for the treatment of primary congenital glaucoma and juvenile open angle glaucoma. In: British Journal of Ophthalmology. 2015 ; Vol. 99, No. 8. pp. 1092-1096.
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abstract = "Background/aims To introduce a novel ab interno 360° trabeculotomy for treating primary congenital glaucoma (PCG) and juvenile open angle glaucoma ( JOAG) and report preliminary results. Methods A retrospective chart review of patients who underwent a gonioscopy assisted transluminal trabeculotomy (GATT) procedure by four of the authors (DSG, OS, RLF and DGG) between October 2011 and October 2013. The surgery was performed in patients ≤30 years old with a dysgenic anterior segment angle and uncontrolled PCG and JOAG. Results Fourteen eyes of 10 patients underwent GATT with follow-up >12 months (12-33 months; mean 20.4). Patients ranged in age from 17 months to 30 years (mean=18.4 years), and five (50{\%}) were female patients. No complications occurred during or following surgery except for early postoperative hyphema in five (36{\%}) of eyes, all cleared by 1 month. The mean intraocular pressure (IOP) decreased from 27.3 to 14.8 mm Hg and the mean number of medications required decreased from 2.6 to 0.86. Five eyes had a drop in IOP ≥15 mm Hg (range 15-39). Conclusions The preliminary results and safety for GATT, a minimally invasive conjunctival sparing circumferential trabeculotomy, are promising and at least equivalent to previous results for ab externo trabeculotomy for the treatment of PCG and JOAG. All eyes in the study were considered a clinical success.",
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