Gonadal function in two Siblings with Fanconi's anemia

Gary Berkovitz, W. H. Zinkham, C. J. Migeon

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

2 siblings with Fanconi's anemia, 1 male and 1 female, aged 22 and 24 years, respectively, were evaluated at the Johns Hopkins Hospital because of short stature and hypogonadism. Plasma levels of somatomedin-C were normal in both patients, suggesting that the production of biologically active growth hormone was normal in these subjects. In addition, measurements of serum gonadotropins and plasma androgens in our patients, along with data accumulated from previous studies in the literature, show that abnormal sexual development in patients with Fanconi's anemia is due to hypergonadotropic hypogonadism.

Original languageEnglish
Pages (from-to)137-141
Number of pages5
JournalHormone Research
Volume19
Issue number3
StatePublished - Jan 1 1984
Externally publishedYes

Fingerprint

Fanconi Anemia
Siblings
Hypogonadism
Sexual Development
Gonadotropins
Insulin-Like Growth Factor I
Androgens
Growth Hormone
Serum

ASJC Scopus subject areas

  • Endocrinology

Cite this

Berkovitz, G., Zinkham, W. H., & Migeon, C. J. (1984). Gonadal function in two Siblings with Fanconi's anemia. Hormone Research, 19(3), 137-141.

Gonadal function in two Siblings with Fanconi's anemia. / Berkovitz, Gary; Zinkham, W. H.; Migeon, C. J.

In: Hormone Research, Vol. 19, No. 3, 01.01.1984, p. 137-141.

Research output: Contribution to journalArticle

Berkovitz, G, Zinkham, WH & Migeon, CJ 1984, 'Gonadal function in two Siblings with Fanconi's anemia', Hormone Research, vol. 19, no. 3, pp. 137-141.
Berkovitz G, Zinkham WH, Migeon CJ. Gonadal function in two Siblings with Fanconi's anemia. Hormone Research. 1984 Jan 1;19(3):137-141.
Berkovitz, Gary ; Zinkham, W. H. ; Migeon, C. J. / Gonadal function in two Siblings with Fanconi's anemia. In: Hormone Research. 1984 ; Vol. 19, No. 3. pp. 137-141.
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