Gold Nephropathy

Raymond R. Tubbs, Rafael Valenzuela, Lawrence J. Mccormack, Marc A. Pohl, Sumner Barenberg

Research output: Contribution to journalLetterpeer-review

4 Scopus citations


To the Editor: The presence of characteristic filamentous, electron-dense cytoplasmic inclusions in various renal cells seems to be the cytologic hallmark of gold-therapy-induced membranous glomerulonephritis. These inclusions have been thought to contain gold; however, this assumption has been substantiated in only two cases.1,2 We should like to report an additional case of gold nephropathy in which the presence of gold in the proximal tubular epithelial cells and interstitial macrophages was demonstrated by x-ray dispersion analysis of the filamentous inclusions. In a 28-year-old black woman who had had severe rheumatoid arthritis for six years proteinuria (6 g per 24 hours). No extract is available for articles shorter than 400 words.

Original languageEnglish (US)
Pages (from-to)1413-1414
Number of pages2
JournalNew England Journal of Medicine
Issue number24
StatePublished - Jun 16 1977

ASJC Scopus subject areas

  • Medicine(all)


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