Gold Nephropathy

Raymond R. Tubbs; Rafael Valenzuela; Lawrence J. Mccormack; Marc A. Pohl; Sumner Barenberg

doi:10.1056/NEJM197706162962419

Gold Nephropathy

Raymond R. Tubbs, Rafael Valenzuela, Lawrence J. Mccormack, Marc A. Pohl, Sumner Barenberg

Pathology

Research output: Contribution to journal › Letter › peer-review

4 Scopus citations

Abstract

To the Editor: The presence of characteristic filamentous, electron-dense cytoplasmic inclusions in various renal cells seems to be the cytologic hallmark of gold-therapy-induced membranous glomerulonephritis. These inclusions have been thought to contain gold; however, this assumption has been substantiated in only two cases.¹^,² We should like to report an additional case of gold nephropathy in which the presence of gold in the proximal tubular epithelial cells and interstitial macrophages was demonstrated by x-ray dispersion analysis of the filamentous inclusions. In a 28-year-old black woman who had had severe rheumatoid arthritis for six years proteinuria (6 g per 24 hours). No extract is available for articles shorter than 400 words.

Original language	English (US)
Pages (from-to)	1413-1414
Number of pages	2
Journal	New England Journal of Medicine
Volume	296
Issue number	24
DOIs	https://doi.org/10.1056/NEJM197706162962419
State	Published - Jun 16 1977

ASJC Scopus subject areas

Medicine(all)

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title = "Gold Nephropathy",

abstract = "To the Editor: The presence of characteristic filamentous, electron-dense cytoplasmic inclusions in various renal cells seems to be the cytologic hallmark of gold-therapy-induced membranous glomerulonephritis. These inclusions have been thought to contain gold; however, this assumption has been substantiated in only two cases.1,2 We should like to report an additional case of gold nephropathy in which the presence of gold in the proximal tubular epithelial cells and interstitial macrophages was demonstrated by x-ray dispersion analysis of the filamentous inclusions. In a 28-year-old black woman who had had severe rheumatoid arthritis for six years proteinuria (6 g per 24 hours). No extract is available for articles shorter than 400 words.",

author = "Tubbs, {Raymond R.} and Rafael Valenzuela and Mccormack, {Lawrence J.} and Pohl, {Marc A.} and Sumner Barenberg",

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doi = "10.1056/NEJM197706162962419",

language = "English (US)",

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TY - JOUR

T1 - Gold Nephropathy

AU - Tubbs, Raymond R.

AU - Valenzuela, Rafael

AU - Mccormack, Lawrence J.

AU - Pohl, Marc A.

AU - Barenberg, Sumner

PY - 1977/6/16

Y1 - 1977/6/16

N2 - To the Editor: The presence of characteristic filamentous, electron-dense cytoplasmic inclusions in various renal cells seems to be the cytologic hallmark of gold-therapy-induced membranous glomerulonephritis. These inclusions have been thought to contain gold; however, this assumption has been substantiated in only two cases.1,2 We should like to report an additional case of gold nephropathy in which the presence of gold in the proximal tubular epithelial cells and interstitial macrophages was demonstrated by x-ray dispersion analysis of the filamentous inclusions. In a 28-year-old black woman who had had severe rheumatoid arthritis for six years proteinuria (6 g per 24 hours). No extract is available for articles shorter than 400 words.

AB - To the Editor: The presence of characteristic filamentous, electron-dense cytoplasmic inclusions in various renal cells seems to be the cytologic hallmark of gold-therapy-induced membranous glomerulonephritis. These inclusions have been thought to contain gold; however, this assumption has been substantiated in only two cases.1,2 We should like to report an additional case of gold nephropathy in which the presence of gold in the proximal tubular epithelial cells and interstitial macrophages was demonstrated by x-ray dispersion analysis of the filamentous inclusions. In a 28-year-old black woman who had had severe rheumatoid arthritis for six years proteinuria (6 g per 24 hours). No extract is available for articles shorter than 400 words.

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DO - 10.1056/NEJM197706162962419

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SP - 1413

EP - 1414

JO - New England Journal of Medicine

JF - New England Journal of Medicine

SN - 0028-4793

IS - 24

ER -

Gold Nephropathy

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