Glycogenin: The primer for mammalian and yeast glycogen synthesis

Joseph Lomako, Wieslawa M. Lomako, William J. Whelan

Research output: Contribution to journalReview articlepeer-review

66 Scopus citations


Glycogen synthesis, whether in mammalian tissue, yeast, or Agrobacterium tumefaciens or other bacteria, is initiated by autoglucosylation of a protein. Initiation in muscle, by a self-glucosylating protein, glycogenin-1, is the most thoroughly studied system, as is described here. These relatively recent findings have prompted a rekindling of interest in the intermediates lying between the primer and mature mammalian glycogen.

Original languageEnglish (US)
Pages (from-to)45-55
Number of pages11
JournalBiochimica et Biophysica Acta - General Subjects
Issue number1-2
StatePublished - Jul 6 2004


  • Autoglucosylation
  • Glycogen synthase primer
  • Glycogenin-1
  • Glycogenin-2
  • Macroglycogen
  • Proglycogen
  • Self-glucosylation

ASJC Scopus subject areas

  • Biochemistry
  • Biophysics
  • Molecular Biology


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