Glyco-S-nitrosothiols, a novel class of NO donor compounds

Johnny Ramirez, Libing Yu, Jun Li, Paul G. Braunschweiger, Peng George Wang

Research output: Contribution to journalArticle

45 Scopus citations

Abstract

Three novel glyco-S-nitrosothiol NO donor compounds 1, 2, and 3 have been synthesized. These compounds outperform S-nitroso-N-acetylpenicillamine (SNAP) in aqueous solubility and stability, with and without EDTA and in the presence or absence of Cu2+.

Original languageEnglish (US)
Pages (from-to)2575-2580
Number of pages6
JournalBioorganic and Medicinal Chemistry Letters
Volume6
Issue number21
DOIs
StatePublished - Nov 5 1996

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ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Pharmaceutical Science
  • Drug Discovery
  • Clinical Biochemistry
  • Organic Chemistry

Cite this

Ramirez, J., Yu, L., Li, J., Braunschweiger, P. G., & Wang, P. G. (1996). Glyco-S-nitrosothiols, a novel class of NO donor compounds. Bioorganic and Medicinal Chemistry Letters, 6(21), 2575-2580. https://doi.org/10.1016/0960-894X(96)00484-2