Glyco-S-nitrosothiols, a novel class of NO donor compounds

Johnny Ramirez, Libing Yu, Jun Li, Paul G. Braunschweiger, Peng George Wang

Research output: Contribution to journalArticlepeer-review

45 Scopus citations

Abstract

Three novel glyco-S-nitrosothiol NO donor compounds 1, 2, and 3 have been synthesized. These compounds outperform S-nitroso-N-acetylpenicillamine (SNAP) in aqueous solubility and stability, with and without EDTA and in the presence or absence of Cu2+.

Original languageEnglish (US)
Pages (from-to)2575-2580
Number of pages6
JournalBioorganic and Medicinal Chemistry Letters
Volume6
Issue number21
DOIs
StatePublished - Nov 5 1996

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Pharmaceutical Science
  • Drug Discovery
  • Clinical Biochemistry
  • Organic Chemistry

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