Glutamate transporters: Using fluorescence to determine structure and to detect conformational changes

H. Peter Larsson, Hans P. Koch

Research output: Contribution to journalArticle

Abstract

Glutamate transporters remove glutamate from the synapse, thereby recycling synaptiallyc released glutamate and maintaining a low extracellular concentration of glutamate. The molecular mechanism underlying glutamate uptake is not understood. We have used fluorescence techniques on human glutamate transporters in order to draw conclusions about the molecular mechanism of glutamate uptake.

Original languageEnglish (US)
Pages (from-to)21-24
Number of pages4
JournalActa Biomedica de l'Ateneo Parmense
Volume77
Issue numberSUPPL. 3
StatePublished - Dec 12 2006
Externally publishedYes

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Keywords

  • EAAT3
  • FRET
  • Sodium binding
  • VCF

ASJC Scopus subject areas

  • Medicine(all)

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