Abstract
There have been several reports of the incorporation of glucosamine into liver glycogen by an intraperitoneal injection of galactosamine, but it has not previously been considered that glucosamine is a normal component of liver glycogen. We now report that glucosamine occurs endogenously in rabbit- and pig-liver glycogens in the amount of about 1 nmol per 10 mg glycogen. Like the glucosamine incorporated by exogenous administration of galactosamine, the endogenous glucosamine takes the place of 1,4-linked α-glucose residues. It is found in both the outer and inner chains of the glycogen molecule.
Original language | English (US) |
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Pages (from-to) | 6-11 |
Number of pages | 6 |
Journal | FEBS letters |
Volume | 194 |
Issue number | 1 |
DOIs | |
State | Published - Jan 1 1986 |
Keywords
- Galactosamine
- Glucosamine
- Kidney glycogen
- Liver glycogen
- N-Methylglucosamine
ASJC Scopus subject areas
- Biochemistry
- Biophysics
- Molecular Biology