Abstract
There have been several reports of the incorporation of glucosamine into liver glycogen by an intraperitoneal injection of galactosamine, but it has not previously been considered that glucosamine is a normal component of liver glycogen. We now report that glucosamine occurs endogenously in rabbit- and pig-liver glycogens in the amount of about 1 nmol per 10 mg glycogen. Like the glucosamine incorporated by exogenous administration of galactosamine, the endogenous glucosamine takes the place of 1,4-linked α-glucose residues. It is found in both the outer and inner chains of the glycogen molecule.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 6-11 |
| Number of pages | 6 |
| Journal | FEBS letters |
| Volume | 194 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 1 1986 |
Keywords
- Galactosamine
- Glucosamine
- Kidney glycogen
- Liver glycogen
- N-Methylglucosamine
ASJC Scopus subject areas
- Biochemistry
- Biophysics
- Molecular Biology
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Cite this
Kirkman, B. R., & Whelan, W. J. (1986). Glucosamine is a normal component of liver glycogen. FEBS letters, 194(1), 6-11. https://doi.org/10.1016/0014-5793(86)80041-2