Glucagon in the Cerebrospinal Fluid

John L. Graner, Carlos Abraira

Research output: Contribution to journalLetter

3 Scopus citations

Abstract

To the Editor: Several peptide hormones have been described in the cerebrospinal fluid.1 In a case of glucagonoma, immunoreactive cerebrospinal fluid glucagon levels have been reported.2 Surprisingly, however, normal reference values for cerebrospinal fluid glucagon levels have never been published. We obtained morning serum and cerebrospinal fluid samples from 19 men who had fasted overnight (age range, 24 to 70 years; mean, 54) in whom lumbar puncture was performed before scheduled myelography; indications for myelography were not a selection factor. Thirteen of the 19 patients studied underwent myelography for sciatica, 2 for arm paresthesias, and 1 each for cervical-spine fracture,.

Original languageEnglish (US)
Pages (from-to)994-995
Number of pages2
JournalNew England Journal of Medicine
Volume312
Issue number15
DOIs
StatePublished - Apr 11 1985

ASJC Scopus subject areas

  • Medicine(all)

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