Glossopharyngeal neuralgia and MS

Alireza Minagar, William A. Sheremata

Research output: Contribution to journalArticlepeer-review

73 Scopus citations


Glossopharyngeal neuralgia (GPN) is characterized by a severe lancinating pain in the posterior pharynx, tonsillar fossa, and base of the tongue. It is induced frequently by swallowing and yawning. GPN has not been described previously in MS patients. The authors report four MS patients with GPN. Three responded to carbamazepine and one resolved during treatment with adrenocorticotrophin hormone (ACTH) and cyclophosphamide. Withdrawal of carbamazepine after 1 week in one patient resulted in recurrence of pain. GPN may be associated with MS and responds to carbamazepine.

Original languageEnglish (US)
Pages (from-to)1368-1370
Number of pages3
Issue number6
StatePublished - Mar 28 2000


  • Carbamazepine
  • Glossopharyngeal neuralgia
  • Multiple sclerosis
  • Pain
  • Trigeminal neuralgia

ASJC Scopus subject areas

  • Neuroscience(all)


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