Abstract
Intraocular pressure (IOP), which causes the lamina cribrosa to bulge backward, produces a pressure gradient along the axoplasm of exiting optic nerve axons, and challenges the circulation, interacts with presently unknown physiologic or anatomic factors to harm the optic nerve and causes loss of vision. Present treatment of glaucoma is limited to efforts to lower IOP. Future treatments may be directed at other contributing anatomic or physiologic abnormalities that permit IOP to be harmful, or at some step in the pathway from insult to mortal injury of the axon or cell body.
| Original language | English |
|---|---|
| Pages (from-to) | 274-278 |
| Number of pages | 5 |
| Journal | Clinical Neuroscience |
| Volume | 4 |
| Issue number | 5 |
| State | Published - Sep 22 1997 |
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Keywords
- Cupping
- Glaucoma
- Optic atrophy
- Optic nerve
ASJC Scopus subject areas
- Neuropsychology and Physiological Psychology
- Neuroscience(all)
Cite this
Glaucomatous optic nerve cupping as an optic neuropathy. / Anderson, Douglas; Cynader, Max S.
In: Clinical Neuroscience, Vol. 4, No. 5, 22.09.1997, p. 274-278.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Glaucomatous optic nerve cupping as an optic neuropathy
AU - Anderson, Douglas
AU - Cynader, Max S.
PY - 1997/9/22
Y1 - 1997/9/22
N2 - Intraocular pressure (IOP), which causes the lamina cribrosa to bulge backward, produces a pressure gradient along the axoplasm of exiting optic nerve axons, and challenges the circulation, interacts with presently unknown physiologic or anatomic factors to harm the optic nerve and causes loss of vision. Present treatment of glaucoma is limited to efforts to lower IOP. Future treatments may be directed at other contributing anatomic or physiologic abnormalities that permit IOP to be harmful, or at some step in the pathway from insult to mortal injury of the axon or cell body.
AB - Intraocular pressure (IOP), which causes the lamina cribrosa to bulge backward, produces a pressure gradient along the axoplasm of exiting optic nerve axons, and challenges the circulation, interacts with presently unknown physiologic or anatomic factors to harm the optic nerve and causes loss of vision. Present treatment of glaucoma is limited to efforts to lower IOP. Future treatments may be directed at other contributing anatomic or physiologic abnormalities that permit IOP to be harmful, or at some step in the pathway from insult to mortal injury of the axon or cell body.
KW - Cupping
KW - Glaucoma
KW - Optic atrophy
KW - Optic nerve
UR - http://www.scopus.com/inward/record.url?scp=0030848852&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0030848852&partnerID=8YFLogxK
M3 - Article
C2 - 9292255
AN - SCOPUS:0030848852
VL - 4
SP - 274
EP - 278
JO - Clinical Neuroscience
JF - Clinical Neuroscience
SN - 1065-6766
IS - 5
ER -