Giant cell tumor of bone in the foot and ankle

R. J. O'Keefe, R. J. O'Donnell, H. Thomas Temple, S. P. Scully, H. J. Mankin

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

Giant cell tumor of bone has been shown to behave more aggressively when located in the wrist and hand. Although nearly 4% of giant cell tumors arise in the foot and ankle, biological features specific to this location have not been identified. In our experience with more than 300 cases of giant cell tumor, 12 arose in the foot and ankle and were followed for more than 2 years. These included nine females and three males ranging in age from 15 to 52 years (mean age, 29.5 years). All patients presented with pain of 5.0 months' mean duration and 9 of 12 tumors demonstrated aggressive radiographic features, including bone erosion and destruction; five had either invasion of a joint or a soft tissue mass present. Unlike the hand, where metacarpal and phalangeal lesions are common, no tumors arose in the forefoot and nine of the tumors were present in the ankle region. Four patients were treated with resection (no recurrence), two with curettage and cement packing (one recurrence), and six with curettage and autologous bone graft (two recurrences), which resulted in an overall recurrence rate of 25%. None of the recurrent tumors have returned after additional treatment, which consisted of curettage and cement packing in two cases and resection in one case. Five tumors (four primary, one recurrent) were treated with local resection and reconstruction with no major complications and with no amputations performed. Thus, giant cell tumors of the foot and ankle can be treated with local procedures, which result in recurrence rates similar to those found in more common locations.

Original languageEnglish
Pages (from-to)617-623
Number of pages7
JournalFoot and Ankle International
Volume16
Issue number10
StatePublished - Jan 1 1995
Externally publishedYes

Fingerprint

Foot Bones
Giant Cell Tumor of Bone
Ankle
Giant Cell Tumors
Curettage
Recurrence
Foot
Neoplasms
Hand
Bone and Bones
Metacarpal Bones
Wrist
Amputation
Joints
Transplants
Pain

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine
  • Surgery

Cite this

O'Keefe, R. J., O'Donnell, R. J., Thomas Temple, H., Scully, S. P., & Mankin, H. J. (1995). Giant cell tumor of bone in the foot and ankle. Foot and Ankle International, 16(10), 617-623.

Giant cell tumor of bone in the foot and ankle. / O'Keefe, R. J.; O'Donnell, R. J.; Thomas Temple, H.; Scully, S. P.; Mankin, H. J.

In: Foot and Ankle International, Vol. 16, No. 10, 01.01.1995, p. 617-623.

Research output: Contribution to journalArticle

O'Keefe, RJ, O'Donnell, RJ, Thomas Temple, H, Scully, SP & Mankin, HJ 1995, 'Giant cell tumor of bone in the foot and ankle', Foot and Ankle International, vol. 16, no. 10, pp. 617-623.
O'Keefe RJ, O'Donnell RJ, Thomas Temple H, Scully SP, Mankin HJ. Giant cell tumor of bone in the foot and ankle. Foot and Ankle International. 1995 Jan 1;16(10):617-623.
O'Keefe, R. J. ; O'Donnell, R. J. ; Thomas Temple, H. ; Scully, S. P. ; Mankin, H. J. / Giant cell tumor of bone in the foot and ankle. In: Foot and Ankle International. 1995 ; Vol. 16, No. 10. pp. 617-623.
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