Giant cell containing lesions of bone and their differential diagnosis

A. E. Rosenberg; G. P. Nielsen

doi:10.1054/cdip.2001.0080

Giant cell containing lesions of bone and their differential diagnosis

A. E. Rosenberg, G. P. Nielsen

Research output: Contribution to journal › Article › peer-review

23 Scopus citations

Abstract

Giant cell rich lesions encompass a relatively large group of biologically and morphologically diverse bone tumours. They are all related to one another by the presence of numerous multinucleated osteoclast-like giant cells. However, they differ from each other by virtue of their clinical and radiographic characteristics and in many cases, their morphology. In select cases, immunohistochemistry may be necessary to make an accurate diagnosis. The importance of correctly identifying these tumours rests on the differences in their treatment and prognosis.

Original language	English (US)
Pages (from-to)	235-246
Number of pages	12
Journal	Current Diagnostic Pathology
Volume	7
Issue number	4
DOIs	https://doi.org/10.1054/cdip.2001.0080
State	Published - Jan 1 2001
Externally published	Yes

Keywords

Aneurysmal bone cyst
Bone tumour
Brown tumour
Chondroblastoma
Giant cell
Giant cell reparative granuloma
Giant cell tumour
Non-ossifying fibroma
Osteosarcoma

ASJC Scopus subject areas

Pathology and Forensic Medicine

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10.1054/cdip.2001.0080

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title = "Giant cell containing lesions of bone and their differential diagnosis",

abstract = "Giant cell rich lesions encompass a relatively large group of biologically and morphologically diverse bone tumours. They are all related to one another by the presence of numerous multinucleated osteoclast-like giant cells. However, they differ from each other by virtue of their clinical and radiographic characteristics and in many cases, their morphology. In select cases, immunohistochemistry may be necessary to make an accurate diagnosis. The importance of correctly identifying these tumours rests on the differences in their treatment and prognosis.",

keywords = "Aneurysmal bone cyst, Bone tumour, Brown tumour, Chondroblastoma, Giant cell, Giant cell reparative granuloma, Giant cell tumour, Non-ossifying fibroma, Osteosarcoma",

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AU - Nielsen, G. P.

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N2 - Giant cell rich lesions encompass a relatively large group of biologically and morphologically diverse bone tumours. They are all related to one another by the presence of numerous multinucleated osteoclast-like giant cells. However, they differ from each other by virtue of their clinical and radiographic characteristics and in many cases, their morphology. In select cases, immunohistochemistry may be necessary to make an accurate diagnosis. The importance of correctly identifying these tumours rests on the differences in their treatment and prognosis.

AB - Giant cell rich lesions encompass a relatively large group of biologically and morphologically diverse bone tumours. They are all related to one another by the presence of numerous multinucleated osteoclast-like giant cells. However, they differ from each other by virtue of their clinical and radiographic characteristics and in many cases, their morphology. In select cases, immunohistochemistry may be necessary to make an accurate diagnosis. The importance of correctly identifying these tumours rests on the differences in their treatment and prognosis.

KW - Aneurysmal bone cyst

KW - Bone tumour

KW - Brown tumour

KW - Chondroblastoma

KW - Giant cell

KW - Giant cell reparative granuloma

KW - Giant cell tumour

KW - Non-ossifying fibroma

KW - Osteosarcoma

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JO - Current Diagnostic Pathology

JF - Current Diagnostic Pathology

SN - 1756-2317

IS - 4

ER -

Giant cell containing lesions of bone and their differential diagnosis

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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