Giant cell containing lesions of bone and their differential diagnosis

A. E. Rosenberg, G. P. Nielsen

Research output: Contribution to journalArticlepeer-review

23 Scopus citations


Giant cell rich lesions encompass a relatively large group of biologically and morphologically diverse bone tumours. They are all related to one another by the presence of numerous multinucleated osteoclast-like giant cells. However, they differ from each other by virtue of their clinical and radiographic characteristics and in many cases, their morphology. In select cases, immunohistochemistry may be necessary to make an accurate diagnosis. The importance of correctly identifying these tumours rests on the differences in their treatment and prognosis.

Original languageEnglish (US)
Pages (from-to)235-246
Number of pages12
JournalCurrent Diagnostic Pathology
Issue number4
StatePublished - Jan 1 2001
Externally publishedYes


  • Aneurysmal bone cyst
  • Bone tumour
  • Brown tumour
  • Chondroblastoma
  • Giant cell
  • Giant cell reparative granuloma
  • Giant cell tumour
  • Non-ossifying fibroma
  • Osteosarcoma

ASJC Scopus subject areas

  • Pathology and Forensic Medicine


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