Abstract
Giant basal cell carcinomas (GBCCs) are large basal cell carcinomas (BCCs; <5 cm) with a greater propensity to invade and metastasize than standard BCCs. The presence of 2 GBCCs in a single individual is rare. We present the case of a 71-year-old Caucasian male with bilateral GBCCs on the dorsal forearms, measuring 130 cm2 and 24 cm2, respectively, that developed over a 21-year period. Over this period, the patient treated the tumors with herbal remedies. Histologic evaluation showed a conventional nodular BCC for both tumors. Computed tomography and magnetic resonance imaging revealed a T4N0M0 stage for the larger lesion. Surgical excision and grafting and reconstruction were offered, but he declined. This case highlights a shared belief in holistic treatments and rejection of Western medical interventions that are common among many patients with GBCC. Studies reporting nonsurgical treatments for GBCCs, including radiotherapy, vismodegib, topical imiquimod, and acitretin are reviewed.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 363-368 |
| Number of pages | 6 |
| Journal | Case Reports in Dermatology |
| Volume | 8 |
| Issue number | 3 |
| DOIs | |
| State | Published - Sep 12 2016 |
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Keywords
- Giant basal cell carcinoma
- Medical therapy
- Nonsurgical treatment
ASJC Scopus subject areas
- Dermatology
Cite this
Giant basal cell carcinomas arising on the bilateral forearms of a patient : A case report and review of nonsurgical treatment options. / Shangraw, Sarah; Stone, Rivka C.; Cho, Jeong Hee; Kirsner, Robert.
In: Case Reports in Dermatology, Vol. 8, No. 3, 12.09.2016, p. 363-368.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - Giant basal cell carcinomas arising on the bilateral forearms of a patient
T2 - A case report and review of nonsurgical treatment options
AU - Shangraw, Sarah
AU - Stone, Rivka C.
AU - Cho, Jeong Hee
AU - Kirsner, Robert
PY - 2016/9/12
Y1 - 2016/9/12
N2 - Giant basal cell carcinomas (GBCCs) are large basal cell carcinomas (BCCs; <5 cm) with a greater propensity to invade and metastasize than standard BCCs. The presence of 2 GBCCs in a single individual is rare. We present the case of a 71-year-old Caucasian male with bilateral GBCCs on the dorsal forearms, measuring 130 cm2 and 24 cm2, respectively, that developed over a 21-year period. Over this period, the patient treated the tumors with herbal remedies. Histologic evaluation showed a conventional nodular BCC for both tumors. Computed tomography and magnetic resonance imaging revealed a T4N0M0 stage for the larger lesion. Surgical excision and grafting and reconstruction were offered, but he declined. This case highlights a shared belief in holistic treatments and rejection of Western medical interventions that are common among many patients with GBCC. Studies reporting nonsurgical treatments for GBCCs, including radiotherapy, vismodegib, topical imiquimod, and acitretin are reviewed.
AB - Giant basal cell carcinomas (GBCCs) are large basal cell carcinomas (BCCs; <5 cm) with a greater propensity to invade and metastasize than standard BCCs. The presence of 2 GBCCs in a single individual is rare. We present the case of a 71-year-old Caucasian male with bilateral GBCCs on the dorsal forearms, measuring 130 cm2 and 24 cm2, respectively, that developed over a 21-year period. Over this period, the patient treated the tumors with herbal remedies. Histologic evaluation showed a conventional nodular BCC for both tumors. Computed tomography and magnetic resonance imaging revealed a T4N0M0 stage for the larger lesion. Surgical excision and grafting and reconstruction were offered, but he declined. This case highlights a shared belief in holistic treatments and rejection of Western medical interventions that are common among many patients with GBCC. Studies reporting nonsurgical treatments for GBCCs, including radiotherapy, vismodegib, topical imiquimod, and acitretin are reviewed.
KW - Giant basal cell carcinoma
KW - Medical therapy
KW - Nonsurgical treatment
UR - http://www.scopus.com/inward/record.url?scp=85006240213&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85006240213&partnerID=8YFLogxK
U2 - 10.1159/000452323
DO - 10.1159/000452323
M3 - Review article
AN - SCOPUS:85006240213
VL - 8
SP - 363
EP - 368
JO - Case Reports in Dermatology
JF - Case Reports in Dermatology
SN - 1662-6567
IS - 3
ER -