@article{45bdef8803ab4491973a7bba4c556a5d,
title = "Getting Closer to an Effective Intervention of Ischemic Stroke: The Big Promise of Stem Cell",
abstract = "Stem cell therapy for ischemic stroke has widely been explored. Results from both preclinical and clinical studies have immensely supported the judicious use of stem cells as therapy. These provide an attractive means for preserving and replacing the damaged brain tissues following an ischemic attack. Since the past few years, researchers have used various types of stem cells to replenish insulted neuronal and glial cells in neurological disorders. In the present review, we discuss different types of stem cells employed for the treatment of ischemic stroke and mechanisms and challenges these cells face once introduced into the living system. Further, we also present different ways to maneuver and overcome challenges to translate the advances made at the preclinical level to clinics.",
keywords = "Cell engineering, Clinical, Ischemic stroke, Neuroprotection, Preclinical, Stem cells",
author = "Deepaneeta Sarmah and Harpreet Kaur and Jackson Saraf and Kanta Pravalika and Avirag Goswami and Kiran Kalia and Anupom Borah and Xin Wang and Dave, {Kunjan R.} and Yavagal, {Dileep R.} and Pallab Bhattacharya",
note = "Funding Information: The authors acknowledge the Department of Science and Technology (DST), Govt. of India, for their financial support through grant (SB/YS/LS-196/2014), International Society for Neurochemistry (ISN) Return Home grant, Department of Pharmaceuticals, Ministry of Chemical and Fertilizers, Govt of India and National Institute of Pharmaceutical Education and Research (NIPER) Ahmedabad, Gandhinagar, India. The authors also want to express their thanks to Boston Children?s Hospital, Harvard Medical School, Boston, MA, USA and the Director, NIPER Ahmedabad, for providing necessary support. The authors declare that they have no conflict of interest. Publisher Copyright: {\textcopyright} 2017, Springer Science+Business Media, LLC. Copyright: Copyright 2018 Elsevier B.V., All rights reserved.",
year = "2018",
month = aug,
day = "1",
doi = "10.1007/s12975-017-0580-0",
language = "English (US)",
volume = "9",
pages = "356--374",
journal = "Translational Stroke Research",
issn = "1868-4483",
publisher = "Springer US",
number = "4",
}