Abstract
Atherosclerotic vascular disease is a systemic process with a common pathophysiology but with different disease manifestations depending on the vascular site. Over the past two decades, significant efforts have gone toward determining the genomic factors contributing to atherosclerotic vascular disease. Substantial information has been generated regarding the genomics of atherosclerotic coronary heart disease, and recently, several genomic analyses have looked at the cerebrovascular and peripheral vascular beds. This article reviews genomic investigations of atherosclerotic vascular disease in the coronary, cerebrovascular, and peripheral arteries. In this review, we have tried to restrict the discussion to studies of premature atherosclerosis, particularly those using non-biased genomic techniques.
| Original language | English |
|---|---|
| Pages (from-to) | 187-193 |
| Number of pages | 7 |
| Journal | Current Atherosclerosis Reports |
| Volume | 12 |
| Issue number | 3 |
| DOIs | |
| State | Published - May 1 2010 |
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Keywords
- Atherosclerosis
- Cerebrovascular disease
- Coronary artery disease
- Genomics
- Peripheral vascular disease
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
Cite this
Genomics of Premature Atherosclerotic Vascular Disease. / Seo, David M; Goldschmidt-Clermont, Pascal; Velazquez, Omaida C; Beecham, Gary W.
In: Current Atherosclerosis Reports, Vol. 12, No. 3, 01.05.2010, p. 187-193.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Genomics of Premature Atherosclerotic Vascular Disease
AU - Seo, David M
AU - Goldschmidt-Clermont, Pascal
AU - Velazquez, Omaida C
AU - Beecham, Gary W
PY - 2010/5/1
Y1 - 2010/5/1
N2 - Atherosclerotic vascular disease is a systemic process with a common pathophysiology but with different disease manifestations depending on the vascular site. Over the past two decades, significant efforts have gone toward determining the genomic factors contributing to atherosclerotic vascular disease. Substantial information has been generated regarding the genomics of atherosclerotic coronary heart disease, and recently, several genomic analyses have looked at the cerebrovascular and peripheral vascular beds. This article reviews genomic investigations of atherosclerotic vascular disease in the coronary, cerebrovascular, and peripheral arteries. In this review, we have tried to restrict the discussion to studies of premature atherosclerosis, particularly those using non-biased genomic techniques.
AB - Atherosclerotic vascular disease is a systemic process with a common pathophysiology but with different disease manifestations depending on the vascular site. Over the past two decades, significant efforts have gone toward determining the genomic factors contributing to atherosclerotic vascular disease. Substantial information has been generated regarding the genomics of atherosclerotic coronary heart disease, and recently, several genomic analyses have looked at the cerebrovascular and peripheral vascular beds. This article reviews genomic investigations of atherosclerotic vascular disease in the coronary, cerebrovascular, and peripheral arteries. In this review, we have tried to restrict the discussion to studies of premature atherosclerosis, particularly those using non-biased genomic techniques.
KW - Atherosclerosis
KW - Cerebrovascular disease
KW - Coronary artery disease
KW - Genomics
KW - Peripheral vascular disease
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UR - http://www.scopus.com/inward/citedby.url?scp=77953620696&partnerID=8YFLogxK
U2 - 10.1007/s11883-010-0104-9
DO - 10.1007/s11883-010-0104-9
M3 - Article
C2 - 20425258
AN - SCOPUS:77953620696
VL - 12
SP - 187
EP - 193
JO - Current Atherosclerosis Reports
JF - Current Atherosclerosis Reports
SN - 1523-3804
IS - 3
ER -