Genomics and Proteomics in Predicting Cancer Outcomes

Alexander A. Parikh, J. Chad Johnson, Nipun B. Merchant

Research output: Contribution to journalReview articlepeer-review

5 Scopus citations

Abstract

Sequencing of the human genome and the acquisition of genomic data combined with advances in genomic and proteomic technologies have fueled a revolution in understanding disease. The combination of genomics and proteomics has provided a unique opportunity to diagnose, classify, and detect malignant disease, to better understand and define the behavior of specific tumors, and to provide direct and targeted therapy. Nevertheless, challenges remain, including integration and standardization of techniques and validation against accepted clinical and pathologic parameters. This article provides a summary of technologies, potential clinical applications, and challenges.

Original languageEnglish (US)
Pages (from-to)257-277
Number of pages21
JournalSurgical oncology clinics of North America
Volume17
Issue number2
DOIs
StatePublished - Apr 2008
Externally publishedYes

ASJC Scopus subject areas

  • Surgery
  • Oncology

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