Genomic value prediction for quantitative traits under the epistatic model

Zhiqiu Hu, Yongguang Li, Xiaohui Song, Yingpeng Han, Xiaodong Cai, Shizhong Xu, Wenbin Li

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

Background: Most quantitative traits are controlled by multiple quantitative trait loci (QTL). The contribution of each locus may be negligible but the collective contribution of all loci is usually significant. Genome selection that uses markers of the entire genome to predict the genomic values of individual plants or animals can be more efficient than selection on phenotypic values and pedigree information alone for genetic improvement. When a quantitative trait is contributed by epistatic effects, using all markers (main effects) and marker pairs (epistatic effects) to predict the genomic values of plants can achieve the maximum efficiency for genetic improvement.Results: In this study, we created 126 recombinant inbred lines of soybean and genotyped 80 makers across the genome. We applied the genome selection technique to predict the genomic value of somatic embryo number (a quantitative trait) for each line. Cross validation analysis showed that the squared correlation coefficient between the observed and predicted embryo numbers was 0.33 when only main (additive) effects were used for prediction. When the interaction (epistatic) effects were also included in the model, the squared correlation coefficient reached 0.78.Conclusions: This study provided an excellent example for the application of genome selection to plant breeding.

Original languageEnglish
Article number15
JournalBMC Genetics
Volume12
DOIs
StatePublished - Jan 26 2011

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Genome
Embryonic Structures
Quantitative Trait Loci
Pedigree
Soybeans

ASJC Scopus subject areas

  • Genetics
  • Genetics(clinical)

Cite this

Genomic value prediction for quantitative traits under the epistatic model. / Hu, Zhiqiu; Li, Yongguang; Song, Xiaohui; Han, Yingpeng; Cai, Xiaodong; Xu, Shizhong; Li, Wenbin.

In: BMC Genetics, Vol. 12, 15, 26.01.2011.

Research output: Contribution to journalArticle

Hu, Zhiqiu ; Li, Yongguang ; Song, Xiaohui ; Han, Yingpeng ; Cai, Xiaodong ; Xu, Shizhong ; Li, Wenbin. / Genomic value prediction for quantitative traits under the epistatic model. In: BMC Genetics. 2011 ; Vol. 12.
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