Genomic revelations of a mutualism: The pea aphid and its obligate bacterial symbiont

Shuji Shigenobu, Alex C.C. Wilson

Research output: Contribution to journalReview article

81 Scopus citations

Abstract

The symbiosis of the pea aphid Acyrthosphion pisum with the bacterium Buchnera aphidicola APS represents the best-studied insect obligate symbiosis. Here we present a refined picture of this symbiosis by linking pre-genomic observations to new genomic data that includes the complete genomes of the eukaryotic and prokaryotic symbiotic partners. In doing so, we address four issues central to understanding the patterns and processes operating at the A. pisum/Buchnera APS interface. These four issues include: (1) lateral gene transfer, (2) host immunity, (3) symbiotic metabolism, and (4) regulation.

Original languageEnglish (US)
Pages (from-to)1297-1309
Number of pages13
JournalCellular and Molecular Life Sciences
Volume68
Issue number8
DOIs
StatePublished - Apr 2011

Keywords

  • Amino acid metabolism
  • Bacteriocyte
  • Buchnera
  • Lateral gene transfer
  • Regulation
  • Symbiosis

ASJC Scopus subject areas

  • Cell Biology
  • Molecular Biology
  • Molecular Medicine
  • Pharmacology
  • Cellular and Molecular Neuroscience

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