Genomic medicine: Bringing biomarkers to clinical medicine

David Seo, Geoffrey S. Ginsburg

Research output: Contribution to journalReview articlepeer-review

18 Scopus citations

Abstract

An important by-product of sequencing the human genome has been the development of a novel 'toolbox' for biomarker discovery and development. Genomic medicine is an emerging discipline in the genome sciences that integrates these tools to interrogate genomic variation in well-defined populations in order to develop predictors of disease susceptibility, progression and drug response. Several important classes of biomarkers result from these analyses which, when translated to clinical medicine and drug development, will have an important impact on human health and disease. This review highlights both the opportunities and challenges in bringing biomarkers into clinical medicine.

Original languageEnglish (US)
Pages (from-to)381-386
Number of pages6
JournalCurrent Opinion in Chemical Biology
Volume9
Issue number4
DOIs
StatePublished - Aug 1 2005
Externally publishedYes

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry

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