Genomic instability and tumor stem cells

James M Grichnik

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Wang et al. point to the existance of a common progenitor tumor stem cell that gives rise to genomically unstable progeny in malignant melanoma. Although it is not known what creates this genomic instability, given the presence of testis antigens in melanoma, it is tempting to speculate that it is caused by a collision of meiotic and mitotic pathways.

Original languageEnglish
Pages (from-to)1214-1216
Number of pages3
JournalJournal of Investigative Dermatology
Volume126
Issue number6
DOIs
StatePublished - Jun 1 2006
Externally publishedYes

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Melanoma-Specific Antigens
Neoplastic Stem Cells
Genomic Instability
Stem cells
Testis
Tumors
Melanoma
Antigens

ASJC Scopus subject areas

  • Dermatology

Cite this

Genomic instability and tumor stem cells. / Grichnik, James M.

In: Journal of Investigative Dermatology, Vol. 126, No. 6, 01.06.2006, p. 1214-1216.

Research output: Contribution to journalArticle

Grichnik, James M. / Genomic instability and tumor stem cells. In: Journal of Investigative Dermatology. 2006 ; Vol. 126, No. 6. pp. 1214-1216.
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