Genitourinary System

Anthony Atala

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

The genitourinary system may be exposed to a variety of possible injuries from the time the fetus develops. Individuals may suffer from congenital disorders, cancer, trauma, infection, inflammation, iatrogenic injuries, or other conditions that may lead to genitourinary organ damage or loss and necessitate eventual reconstruction. Whenever there is a lack of native urologic tissue, reconstruction may be performed with native non-urologic tissues (skin, gastrointestinal segments, or mucosa from multiple body sites), homologous tissues (cadaver fascia, cadaver or donor kidney), heterologous tissues (bovine collagen), or artificial materials (silicone, polyurethane, Teflon). The tissues used for reconstruction may lead to complications because of their inherently different functional parameters. In most cases, the replacement of lost or deficient tissues with functionally equivalent tissues would improve the outcome for these patients. This goal may be attainable with the use of tissue-engineering techniques.

Original languageEnglish
Title of host publicationPrinciples of Tissue Engineering: Fourth Edition
PublisherElsevier Inc.
Pages1157-1167
Number of pages11
ISBN (Print)9780123983589
DOIs
StatePublished - Nov 1 2013
Externally publishedYes

Fingerprint

Urogenital System
Tissue
Cadaver
Wounds and Injuries
Congenital, Hereditary, and Neonatal Diseases and Abnormalities
Polyurethanes
Fascia
Polytetrafluoroethylene
Silicones
Tissue Engineering
Tissue engineering
Skin
Mucous Membrane
Fetus
Collagen
Tissue Donors
Inflammation
Kidney
Infection

Keywords

  • Acellular tissue matrix
  • Biomaterial
  • Cells
  • Collagen
  • Extracellular matrix
  • Genitourinary system
  • Matrices
  • Naturally derived
  • Reconstruction
  • Synthetic polymer
  • Tissue
  • Tissue engineering

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Atala, A. (2013). Genitourinary System. In Principles of Tissue Engineering: Fourth Edition (pp. 1157-1167). Elsevier Inc.. https://doi.org/10.1016/B978-0-12-398358-9.00053-7

Genitourinary System. / Atala, Anthony.

Principles of Tissue Engineering: Fourth Edition. Elsevier Inc., 2013. p. 1157-1167.

Research output: Chapter in Book/Report/Conference proceedingChapter

Atala, A 2013, Genitourinary System. in Principles of Tissue Engineering: Fourth Edition. Elsevier Inc., pp. 1157-1167. https://doi.org/10.1016/B978-0-12-398358-9.00053-7
Atala A. Genitourinary System. In Principles of Tissue Engineering: Fourth Edition. Elsevier Inc. 2013. p. 1157-1167 https://doi.org/10.1016/B978-0-12-398358-9.00053-7
Atala, Anthony. / Genitourinary System. Principles of Tissue Engineering: Fourth Edition. Elsevier Inc., 2013. pp. 1157-1167
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