Genetics of the antibody response to dextran in mice

Bonnie Blomberg, William R. Geckeler, Martin Weigert

Research output: Contribution to journalArticle

237 Scopus citations

Abstract

The immune response to dextran having the α-1,3 linkage may be under the control of antibody structural genes. Mice that respond well to this antigen produce antibody restricted with respect to light chain class (λ) and to an antigenie determinant resulting from a particular heavy and light chain interaction. The response to dextran is controlled by a locus linked to the-heavy chain locus.

Original languageEnglish (US)
Pages (from-to)178-180
Number of pages3
JournalScience
Volume177
Issue number4044
DOIs
StatePublished - Jan 1 1972

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