Genetically engineered whole-cell sensing systems: coupling biological recognition with reporter genes

Sylvia Daunert, Gary Barrett, Jessika S. Feliciano, Ranjit S. Shetty, Suresh Shrestha, Wendy Smith-Spencer

Research output: Contribution to journalArticlepeer-review

324 Scopus citations

Abstract

A review is carried, covering the design, development, and analytical applications of genetically engineered cell-based biosensing systems employing reporter genes. First, an overview is given of the chemical reactions and structural properties of the reporter genes currently used in cell-based biosensing arrays. The advantages and disadvantages of these genes as reporter are also discussed.

Original languageEnglish (US)
Pages (from-to)2705-2738
Number of pages34
JournalChemical Reviews
Volume100
Issue number7
DOIs
StatePublished - Jul 1 2000
Externally publishedYes

ASJC Scopus subject areas

  • Chemistry(all)

Fingerprint Dive into the research topics of 'Genetically engineered whole-cell sensing systems: coupling biological recognition with reporter genes'. Together they form a unique fingerprint.

Cite this