Genetically engineered whole-cell sensing systems: coupling biological recognition with reporter genes

Sylvia Daunert, Gary Barrett, Jessika S. Feliciano, Ranjit S. Shetty, Suresh Shrestha, Wendy Smith-Spencer

Research output: Contribution to journalArticle

314 Citations (Scopus)

Abstract

A review is carried, covering the design, development, and analytical applications of genetically engineered cell-based biosensing systems employing reporter genes. First, an overview is given of the chemical reactions and structural properties of the reporter genes currently used in cell-based biosensing arrays. The advantages and disadvantages of these genes as reporter are also discussed.

Original languageEnglish
Pages (from-to)2705-2738
Number of pages34
JournalChemical Reviews
Volume100
Issue number7
DOIs
StatePublished - Jul 1 2000
Externally publishedYes

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Genes
Structural properties
Chemical reactions

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Daunert, S., Barrett, G., Feliciano, J. S., Shetty, R. S., Shrestha, S., & Smith-Spencer, W. (2000). Genetically engineered whole-cell sensing systems: coupling biological recognition with reporter genes. Chemical Reviews, 100(7), 2705-2738. https://doi.org/10.1021/cr990115p

Genetically engineered whole-cell sensing systems : coupling biological recognition with reporter genes. / Daunert, Sylvia; Barrett, Gary; Feliciano, Jessika S.; Shetty, Ranjit S.; Shrestha, Suresh; Smith-Spencer, Wendy.

In: Chemical Reviews, Vol. 100, No. 7, 01.07.2000, p. 2705-2738.

Research output: Contribution to journalArticle

Daunert, S, Barrett, G, Feliciano, JS, Shetty, RS, Shrestha, S & Smith-Spencer, W 2000, 'Genetically engineered whole-cell sensing systems: coupling biological recognition with reporter genes', Chemical Reviews, vol. 100, no. 7, pp. 2705-2738. https://doi.org/10.1021/cr990115p
Daunert, Sylvia ; Barrett, Gary ; Feliciano, Jessika S. ; Shetty, Ranjit S. ; Shrestha, Suresh ; Smith-Spencer, Wendy. / Genetically engineered whole-cell sensing systems : coupling biological recognition with reporter genes. In: Chemical Reviews. 2000 ; Vol. 100, No. 7. pp. 2705-2738.
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