Genetically engineered whole-cell sensing systems: coupling biological recognition with reporter genes

Sylvia Daunert, Gary Barrett, Jessika S. Feliciano, Ranjit S. Shetty, Suresh Shrestha, Wendy Smith-Spencer

Research output: Contribution to journalArticle

319 Scopus citations

Abstract

A review is carried, covering the design, development, and analytical applications of genetically engineered cell-based biosensing systems employing reporter genes. First, an overview is given of the chemical reactions and structural properties of the reporter genes currently used in cell-based biosensing arrays. The advantages and disadvantages of these genes as reporter are also discussed.

Original languageEnglish (US)
Pages (from-to)2705-2738
Number of pages34
JournalChemical Reviews
Volume100
Issue number7
DOIs
StatePublished - Jul 1 2000
Externally publishedYes

ASJC Scopus subject areas

  • Chemistry(all)

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  • Cite this

    Daunert, S., Barrett, G., Feliciano, J. S., Shetty, R. S., Shrestha, S., & Smith-Spencer, W. (2000). Genetically engineered whole-cell sensing systems: coupling biological recognition with reporter genes. Chemical Reviews, 100(7), 2705-2738. https://doi.org/10.1021/cr990115p