Genetic polymorphisms related to behavioral approach and behavioral inhibition scales

Sheri L. Johnson, Charles S Carver, Jutta Joormann, Michael Cuccaro

Research output: Contribution to journalArticle

8 Scopus citations


Genetic polymorphisms relevant to behavioral approach and behavioral inhibition are examined, using a polygenic approach while also considering the role of early adversity. Undergraduates (N. =. 343) completed the well-validated Behavioral Inhibition System/Behavioral Activation System (BIS/BAS) scales and provided blood for genotyping. The BDNF met allele was related to higher BIS scores. OPRM1 status interacted with a measure of early adversity to predict the BAS Reward Responsiveness subscale. Results provide additional support for the validity of the BIS/BAS scales, and suggest combined genetic and environmental influences on the development of these traits.

Original languageEnglish (US)
Article number7047
Pages (from-to)251-255
Number of pages5
JournalPersonality and Individual Differences
StatePublished - Jan 1 2016



  • BDNF
  • Behavioral approach
  • Behavioral inhibition
  • Genetic polymorphism
  • OPRM1

ASJC Scopus subject areas

  • Psychology(all)

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