Abstract
Genetic polymorphisms relevant to behavioral approach and behavioral inhibition are examined, using a polygenic approach while also considering the role of early adversity. Undergraduates (N. =. 343) completed the well-validated Behavioral Inhibition System/Behavioral Activation System (BIS/BAS) scales and provided blood for genotyping. The BDNF met allele was related to higher BIS scores. OPRM1 status interacted with a measure of early adversity to predict the BAS Reward Responsiveness subscale. Results provide additional support for the validity of the BIS/BAS scales, and suggest combined genetic and environmental influences on the development of these traits.
| Original language | English (US) |
|---|---|
| Article number | 7047 |
| Pages (from-to) | 251-255 |
| Number of pages | 5 |
| Journal | Personality and Individual Differences |
| Volume | 88 |
| DOIs | |
| State | Published - Jan 1 2016 |
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Keywords
- BDNF
- Behavioral approach
- Behavioral inhibition
- Genetic polymorphism
- OPRM1
ASJC Scopus subject areas
- Psychology(all)
Cite this
Genetic polymorphisms related to behavioral approach and behavioral inhibition scales. / Johnson, Sheri L.; Carver, Charles S; Joormann, Jutta; Cuccaro, Michael.
In: Personality and Individual Differences, Vol. 88, 7047, 01.01.2016, p. 251-255.Research output: Contribution to journal › Article
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TY - JOUR
T1 - Genetic polymorphisms related to behavioral approach and behavioral inhibition scales
AU - Johnson, Sheri L.
AU - Carver, Charles S
AU - Joormann, Jutta
AU - Cuccaro, Michael
PY - 2016/1/1
Y1 - 2016/1/1
N2 - Genetic polymorphisms relevant to behavioral approach and behavioral inhibition are examined, using a polygenic approach while also considering the role of early adversity. Undergraduates (N. =. 343) completed the well-validated Behavioral Inhibition System/Behavioral Activation System (BIS/BAS) scales and provided blood for genotyping. The BDNF met allele was related to higher BIS scores. OPRM1 status interacted with a measure of early adversity to predict the BAS Reward Responsiveness subscale. Results provide additional support for the validity of the BIS/BAS scales, and suggest combined genetic and environmental influences on the development of these traits.
AB - Genetic polymorphisms relevant to behavioral approach and behavioral inhibition are examined, using a polygenic approach while also considering the role of early adversity. Undergraduates (N. =. 343) completed the well-validated Behavioral Inhibition System/Behavioral Activation System (BIS/BAS) scales and provided blood for genotyping. The BDNF met allele was related to higher BIS scores. OPRM1 status interacted with a measure of early adversity to predict the BAS Reward Responsiveness subscale. Results provide additional support for the validity of the BIS/BAS scales, and suggest combined genetic and environmental influences on the development of these traits.
KW - BDNF
KW - Behavioral approach
KW - Behavioral inhibition
KW - Genetic polymorphism
KW - OPRM1
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U2 - 10.1016/j.paid.2015.09.024
DO - 10.1016/j.paid.2015.09.024
M3 - Article
AN - SCOPUS:84942543628
VL - 88
SP - 251
EP - 255
JO - Personality and Individual Differences
JF - Personality and Individual Differences
SN - 0191-8869
M1 - 7047
ER -